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This study found that a topical 5% phenytoin solution, applied twice daily for 16 weeks, significantly improved total hair count and hair density in men with androgenetic alopecia, with mild and transient side effects observed.

This study found that topical finasteride significantly increased hair count in men with androgenetic alopecia compared to placebo while maintaining similar efficacy to oral finasteride but with lower systemic exposure and a reduced impact on serum DHT levels, potentially minimizing sexual side effects.

This review discusses the topical use of systemic drugs for cutaneous disorders and reports a lack of strong evidence from randomized controlled trials, highlighting the need for larger comparative effectiveness studies.

This review highlights drug repositioning strategies for discovering new treatments for skin conditions and reports no new clinical results, emphasizing the integration of systematic methods with advances in molecular biology and omics.

In this animal study, topical diazoxide treatment led to increased hair thickness and follicle growth in bald stumptailed macaques without causing notable systemic side effects.