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      learn Fluridil

      a topical anti-androgen with less systemic involvement

      learn Spironolactone

      powerful topical and oral anti-androgen used mostly by women

      learn Clascoterone

      a novel topical treatment that inhibits DHT on androgen receptors

      learn RU58841

      a potent but unapproved and potentially problematic topical anti-androgen

      learn Melatonin

      hormone commonly taken for sleep aid has some topical benefits for hair

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      community Fats on your Head to Stop Hair Loss?

      in Research/Science  138 upvotes 9 months ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

      community Topical minoxidil 3 months results

      in Progress Pictures  624 upvotes 2 years ago
      This conversation is about a user named "mr_mime125" who experienced results from using topical finasteride (0.1%) and minoxidil (5%) solution 1.5 ml twice a day for the first two months followed by just minoxidil (5%) 1 ml once a day in the last month, resulting in a drastic improvement to their hairline. Other users discussed their progress while asking questions and offering encouragement.

      community Group Buy for MR antagonist finerenone

      in Product  11 upvotes 1 year ago
      User discusses group buy for finerenone, a third-gen mineralocorticoid antagonist for hair loss treatment. Finerenone inhibits TGFb, NOX, and ROS, and improves renal and cardiac function; topical dose should be no more than 10mg per day.