November 2022 in “Pakistan Armed Forces Medical Journal” This study found that topical liquid nitrogen improved pain tolerance during intradermal platelet-rich plasma therapy in androgenic alopecia compared to normal saline, although patient satisfaction did not significantly differ between groups.
6 citations
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July 2023 in “Journal of Drugs in Dermatology” This narrative review found that cryotherapy resulted in approximately 60% hair regrowth response in alopecia areata patients, with some evidence suggesting lower relapse rates compared to intralesional steroid injection, although no statistically significant difference in efficacy was identified.
April 2021 in “Sohag Medical Journal” This research suggests that superficial cryotherapy is a safe and nearly as effective alternative to topical steroids and PUVA therapy for treating alopecia areata, especially in children.
July 1988 in “Journal of The American Academy of Dermatology” This article reviews therapeutic advances published between December 1986 and December 1987 but reports no new research findings; readers are advised to consult the original articles before considering new therapies.
15 citations
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October 2006 in “Journal of the American Academy of Dermatology” This case report describes subcutaneous emphysema in a patient's forearm as a rare complication of liquid nitrogen spray used on hypertrophic actinic keratosis, resolving spontaneously within a day.