March 2014 in “Journal of The American Academy of Dermatology” A botanical extract may help manage hair loss from chemotherapy by preventing cell death in hair follicles.
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October 2024 in “Dermatology Practical & Conceptual” In this double-blind randomized controlled trial, both rosemary extract lotion and 2% ketoconazole lotion were effective for treating scalp seborrheic dermatitis, but rosemary lotion reduced itching more significantly, while ketoconazole was more effective in reducing dandruff.
October 2025 in “JCI Insight” In a mouse model, this study found that an ethanol-based rosemary extract speeds up wound healing and reduces scarring by activating the TRPA1 nociceptor in sensory neurons, with carnosic acid identified as a key component.
April 2013 in “Cancer Research” This study found that a botanical extract increased Bcl-2 levels and improved the anagen-to-telogen hair ratio in men with androgenetic alopecia, suggesting potential for managing chemotherapy-induced alopecia.
In this preclinical study, PA-011 derived from Periplaneta americana showed significant hair regrowth effects in androgenetic alopecia mouse models by inhibiting inflammation and oxidative stress, activating hair follicle stem cell proliferation, and normalizing skin microbiota, suggesting promise as an AGA treatment.