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Research

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research Emerging Topical and Systemic JAK Inhibitors in Dermatology

277 citations , December 2019 in “Frontiers in Immunology”

This review discusses the immunological basis and development of Janus kinase inhibitors for treating skin diseases and reports no new clinical findings.

research Polymeric nanoparticles‐based topical delivery systems for the treatment of dermatological diseases

263 citations , February 2013 in “Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology”

This review discusses nanoparticle-based topical delivery systems for treating skin diseases and presents no new clinical findings; it emphasizes natural polymer-based nanoparticles and future applications like targeted drug delivery.

research A randomized, placebo-controlled trial of 5% and 2% topical minoxidil solutions in the treatment of female pattern hair loss

219 citations , March 2004 in “Journal of The American Academy of Dermatology”

In this 48-week trial, 5% topical minoxidil was more effective than both 2% minoxidil and placebo in promoting hair growth in women with female pattern hair loss, with notable improvements in nonvellus hair count and hair growth assessments.

research Liposomes and Niosomes as Topical Drug Delivery Systems

205 citations , January 2005 in “Skin pharmacology and physiology”

This review discusses how liposomes and niosomes can enhance drug penetration in topical delivery systems and emphasizes the importance of their specific composition, size, and type, but it reports no new results.

research Lecithin organogels as a potential phospholipid-structured system for topical drug delivery: A review

202 citations , June 2005 in “Aaps Pharmscitech”

This review discusses the potential of lecithin organogels for improving topical drug delivery and presents no new experimental results; the authors highlight their stability and low skin irritancy as advantages.

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Community Join

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community Topical Minxodil stoped working- switching to oral?

1 upvotes 1 week ago

The user experienced reduced effectiveness of topical Minoxidil after three years and is considering switching to oral Minoxidil, while also using finasteride for six months without significant hair regrowth. Suggestions include continuing finasteride for longer, considering oral Minoxidil, or switching to dutasteride for better results.

community Topical Finasteride dose doubts

1 week ago

A user is considering using a topical compound of 0.25% finasteride and 5% minoxidil for hair loss, concerned about side effects experienced with oral finasteride. Other users suggest starting with a lower concentration and possibly diluting the solution to minimize side effects.

community Topical Minoxidil causes this face puffiness?

32 upvotes 1 week ago

A user is concerned about facial puffiness potentially caused by minoxidil, but others suggest it might be due to aging, lighting, or water retention. The user has been using topical minoxidil for 8 months and recently started oral minoxidil, noticing changes in facial appearance.

community Topical finasteride - Can anyone here share their results?

4 upvotes 1 week ago

Topical finasteride combined with oral minoxidil is used by some for hair loss, with mixed results; some users report success while others find it difficult to apply. Alternatives like oral finasteride and microneedling are also considered, with some users experiencing hair stabilization and new growth.

community TOPICAL dut vs. ORAL fin: more effective?

4 upvotes 2 weeks ago

Switching from oral finasteride to topical dutasteride for hair loss, with mixed experiences reported; some users found oral treatments more effective. Combining treatments like dutasteride and minoxidil was also suggested for better results.

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Learn

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learn Finasteride

Topical or oral? Choosing between pills and lotions according to your case. Topical finasteride offers localized treatment with fewer systemic side effects than oral finasteride.

learn Cetirizine

Is topical cetirizine effective for androgenetic alopecia in women? Topical cetirizine is not an approved product and its use for female-pattern hair loss is off-label. The evidence is one small unblinded pilot study in mixed-sex patients and one randomized trial in 66 women where cetirizine was added to minoxidil; it is unproven on its own.

learn Estradiol

How does topical Estradiol compare to oral Estradiol in treating alopecia? Topical estradiol delivers hormone to the scalp with less systemic exposure, but evidence is thin and it is still a hormone. It needs a doctor's supervision, and people with estrogen-sensitive cancers must not use it without medical approval.