research Targeting Host Cell Proteases as a Potential Treatment Strategy to Limit the Spread of SARS-CoV-2 in the Respiratory Tract
Blocking enzymes that help the virus enter cells could be a promising way to treat COVID-19.
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5 / 222 results research Spiking Dependence of SARS-CoV-2 Pathogenicity on TMPRSS2
This review explored the role of the Transmembrane Serine Protease 2 (TMPRSS2) in influencing the susceptibility and pathogenicity of SARS-CoV-2 across different population groups. It highlighted that the cleavage of the viral spike protein by TMPRSS2 is crucial for viral entry into host cells, and variations in the expression of the TMPRSS2 gene among ethnic groups could impact COVID-19 infection rates and outcomes. The review also discussed potential treatments involving TMPRSS2 protease blockers and inhibitors as promising strategies for managing COVID-19.
research Cutaneous Signs in COVID-19 Patients: A Review
COVID-19 can cause different skin symptoms that may help with early diagnosis and show how severe the disease is.
research Are the Cutaneous Manifestations During or Due to SARS-CoV-2 Infection/COVID-19 Frequent or Not? Revision of Possible Pathophysiologic Mechanisms
Skin problems in COVID-19 patients are rare and may be due to the body's complex immune response or blood clotting issues.
research Basic Mechanisms of SARS-CoV-2 Infection: Implications for Endocrine Systems
SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.
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1 / 1 resultscommunity Adrogens and Covid-19
The possible increased risk of severe Covid-19 cases in men due to higher androgen levels, and how taking medications such as finasteride, dutasteride, spironolactone, enzalutamide, or canabidiol might help mitigate the severity of the disease.