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    GlossaryTissue Plasminogen Activator

    protein that dissolves blood clots by activating plasminogen

    Tissue Plasminogen Activator (TPA) is a protein involved in the breakdown of blood clots. It converts plasminogen, an inactive protein in the blood, into plasmin, an enzyme that dissolves clots. TPA is often used in medical treatments to quickly dissolve clots in patients experiencing heart attacks or strokes.

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      community How You Can Help Speed Up the Verteporfin Trials

      in Research/Science  185 upvotes 1 year ago
      The post discusses speeding up verteporfin trials for hair loss treatment. The original poster, involved in the trials, requests help in crowdsourcing doctor emails to spread awareness and gather more support for the trials.

      community Painkillers May Block Minoxidil

      in Research/Science  14 upvotes 5 months ago
      Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.

      community DUPA, Non Responders and Connective Tissue Disorders

      in Research/Science  7 upvotes 2 months ago
      A 27-year-old male with diffuse hair loss, including the donor area, did not respond to finasteride, dutasteride, or minoxidil. He suspects his hair loss may be linked to a mild connective tissue disorder, possibly affecting the structural support of hair follicles, rather than being purely hormonal.

      community We need actual hair loss studies on Epristeride

      in Research/Science  6 upvotes 10 months ago
      Epristeride is a selective 5 alpha reductase type 2 inhibitor that may reduce scalp DHT similarly to finasteride, with potentially fewer side effects. It is suggested that combining epristeride with finasteride or dutasteride could enhance hair loss treatment effectiveness.