This study reported that microneedle-assisted delivery of PEGylated recombinant human fusion collagen significantly improved hair regrowth and density in an androgenetic alopecia mouse model and in a small clinical trial with AGA patients, suggesting potential efficacy and safety for this treatment approach.
2 citations
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January 2016 in “Archives of Aesthetic Plastic Surgery”
This article reviews methods for restoring the temporal peaks of hair and highlights a technique that produces variable density for a more natural look, but reports no new clinical results.
Oleic acid and ethanol are being considered for hair regrowth, with some users planning to self-experiment. There is skepticism about their effectiveness, and ongoing use of treatments like finasteride and minoxidil is mentioned.
Creatine may increase DHT levels, potentially causing hair loss in some people, though experiences vary. Treatments like finasteride or minoxidil are suggested to manage potential hair loss.
A user in Germany struggles to get a finasteride prescription despite trying multiple doctors and apps, only receiving minoxidil. Other users suggest alternative sources like Zava.med, EU doctor App, and buying from pharmacies abroad.
Creatine does not directly cause hair loss but may increase DHT levels, potentially worsening hair loss in those predisposed to male pattern baldness. Users have mixed experiences, with some reporting increased shedding and others seeing no effect.
A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.
Patchy hair loss or alopecia areata: is there any evidence for Baicapil?There is no published trial of Baicapil in alopecia areata. The anti-inflammatory and hair-density claims come from the ingredient's manufacturer and from laboratory work on its plant extracts; none of it involved people with autoimmune patchy hair loss.
Is there any downtime after a hair transplant?Clinics usually say desk work is possible within a few days, but redness and scabs can last 1 to 2 weeks and strenuous activity is restricted for longer.