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    Glossary5α-reductase (testosterone 5-alpha-reductase)

    enzyme converting testosterone into potent dihydrotestosterone (DHT)

    5α-reductase is an enzyme that converts testosterone into dihydrotestosterone (DHT), a more potent androgen hormone. This enzyme plays a significant role in various biological processes, including the development of male characteristics and the regulation of hair growth. Inhibitors of 5α-reductase, such as finasteride, are commonly used to treat conditions like male pattern baldness and benign prostatic hyperplasia.

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    Products matching "testosterone 5-alpha-reductase"

    Tracking 2 products like 96 MinoDuta and 273 Finasterid Kaufen from by companies like MinoxidilMax and Deutschemedz. View all 2 products »

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      learn Finasteride

      Frontline, gold standard treatment for combatting androgenic alopecia

      learn Saw Palmetto

      a natural and far less effective alternative to Finasteride

      learn Azelaic Acid

      acid used for antimicrobial, anti-inflammatory and anti-androgenic properties

      learn Rosemary

      herb and oil with stimulant, circulatory, anti-inflammatory and antioxidant properties

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      community A hair model who does beauty ads and has 3 million followers claims he went from almost a Norwood 3 to a perfect hairline in 8 months on only Minoxidil and Rosemary oil. Curious, what are people’s thoughts?

      in Chat 1 year ago
      This conversation discusses the results of a model who claims he went from almost a Norwood 3 to a perfect hairline in 8 months using only Minoxidil and Rosemary oil. The replies suggest that this could be realistic but long-term results would require additional treatments like finasteride or other medications to prevent further hair loss.

      community how about progesterone cream?

      in Research/Science  21 upvotes 6 months ago
      Progesterone cream might help with hair loss by inhibiting DHT production and suppressing prolactin, which can increase DHT. Some dermatologists have used progesterone for hair loss treatment, and it has been effective, sometimes combined with minoxidil, finasteride, and hydrocortisone.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 2 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.