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research Transcriptomic profiling in Silurana tropicalis testes exposed to finasteride

8 citations , February 2014 in “General and Comparative Endocrinology”

In this study, exposure to the drug finasteride in Silurana tropicalis significantly increased testosterone levels in liver and testis tissues and altered gene expression related to male reproduction and oxidative stress.

research SEXUAL DIMORPHISM IN MAMMALS

138 citations , November 1974 in “Biological reviews/Biological reviews of the Cambridge Philosophical Society”

This review explores the structural and functional sex differences in mammals beyond reproductive organs, highlighting variations in life expectancy, organ size, metabolism, and immune function, but it reports no new results.

research SHISA6 Confers Resistance to Differentiation-Promoting Wnt/β-Catenin Signaling in Mouse Spermatogenic Stem Cells

77 citations , February 2017 in “Stem Cell Reports”

This study found that activation of Wnt/β-catenin signaling in mouse testes promotes spermatogonial differentiation and reduces the stem cell pool, with SHISA6 inhibiting this process and maintaining stem cell characteristics.

research EZH2-mediated inhibition of microRNA-22 promotes differentiation of hair follicle stem cells by elevating STK40 expression

12 citations , July 2020 in “Aging”

This study found that the enhancer of zeste homolog 2 (EZH2) may promote hair growth by increasing STK40 expression and facilitating hair follicle stem cell proliferation and differentiation.

Paracrine Secreted Frizzled-Related Protein 4 Inhibits Melanocyte Differentiation in Hair Follicle

research Paracrine Secreted Frizzled-Related Protein 4 Inhibits Melanocytes Differentiation in Hair Follicle

8 citations , January 2017 in “Stem Cells International”

This study found that overexpression of sFRP4 in skin cells reduces Wnt signaling activation, leading to decreased melanocyte differentiation in regenerating hair follicles.

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community The Real Cause Of Androgenetic Alopecia

675 upvotes 1 year ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community Janoshik tests of Actifolic RU-58841 powder and GhK-Cu peptide

10 upvotes 7 months ago

Actifolic RU-58841 powder and GhK-Cu peptide were tested and found to be accurate. The user is satisfied with the product's authenticity for hair loss treatment.

community Hormone tests to decide on oral fin

4 upvotes 1 year ago

The conversation discusses starting low-dose oral finasteride for hair loss, considering hormone levels and potential side effects like gynecomastia. Suggestions include using DIM for estradiol, vitamin B6 for prolactin, and lifestyle changes to optimize hormone profiles before starting treatment.

community Finasteride increased my Test from 900 ng/dl to 1200

in Finasteride/Dutasteride 90 upvotes 7 months ago

Finasteride increased testosterone levels from 900 ng/dl to 1200 ng/dl without side effects, improving hair condition. Access to finasteride and minoxidil varies by country, with some places requiring prescriptions and others offering easy access.

community Finasteride and hormonal tests

in Finasteride/Dutasteride 8 months ago

A user has been taking finasteride 1mg for 10 years without side effects but is concerned about high estradiol levels affecting weight loss. Another user suggests using estradiol blockers under medical supervision to manage the levels.

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