January 2024 in “INSTITUTIONAL REPOSITORY OF ODESSA NATIONAL UNIVERSITY NAMED I.I. Mechnykova (Odesa I.I.Mechnikov National University)” This article discusses the causes and consequences of hyperestrogenism in men of reproductive age and emphasizes the need for proper hormonal testing and treatment, reporting no new clinical findings.
October 2022 in “Endocrine journal” In this study of male patients with 46,XY 5α-reductase type 2 deficiency, DHT therapy was effective in achieving penile enlargement during infancy, while testosterone replacement therapy proved more beneficial during puberty, possibly due to increased conversion to DHT.
12 citations
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January 2016 in “Endocrinology, diabetes & metabolism case reports” This report describes a 19-year-old male with 49,XXXXY syndrome receiving testosterone replacement therapy, which led to improvements in reproductive development, metabolism, and social interaction after a year of treatment.
163 citations
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November 1976 in “Annals of Internal Medicine” This study found that adults with sickle cell anemia exhibited androgen deficiency due to primary testicular failure, and there was a significant correlation between erythrocyte zinc levels and serum testosterone.
September 2006 in “Data Archiving and Networked Services (DANS)” This article discusses the testosterone and estradiol levels in men, examining their roles and suggesting the need for better understanding to differentiate between normal and abnormal levels related to androgen deficiency symptoms, without reporting new clinical results.