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    Did you mean Terminal Differentiation?
    Glossary Terminal Differentiation

    cell's final development into a specialized, non-dividing state

    Terminal differentiation is the process by which a cell undergoes its final stage of development, becoming a specialized cell type with a specific function, such as a skin cell or a neuron. Once a cell has terminally differentiated, it typically loses the ability to divide and produce new cells, focusing instead on performing its specialized role. This process is crucial for the proper functioning of tissues and organs in the body.

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    1. Non-invasive human skin transcriptome analysis using mRNA in skin surface lipids bioRxiv (Cold Spring Harbor Laboratory) · 2021 · 2 citations
    2. Chapter 3 Expression and Modification of Keratins During Terminal Differentiation of Mammalian Epidermis 1987 · 81 citations
    3. Human Trichohyalin Gene Is Clustered with the Genes for Other Epidermal Structural Proteins and Calcium-Binding Proteins at Chromosomal Locus 1q21 1993
    4. 874 Chromatin architectural protein CTCF controls epidermal barrier formation, hair follicle fate maintenance and suppresses inflammatory responses in the skin epithelium Journal of Investigative Dermatology · 2017
    5. Deciphering a Message from the Nucleus: How Transcription Factors and Spatial Chromatin Interactions Orchestrate Epidermal Differentiation 2023
    6. Cyclosporin A-induced hair growth in mice is associated with inhibition of calcineurin-dependent activation of NFAT in follicular keratinocytes American Journal of Physiology-cell Physiology · 2003 · 57 citations
    7. p63 Regulates Human Keratinocyte Proliferation via MYC-regulated Gene Network and Differentiation Commitment through Cell Adhesion-related Gene Network Journal of Biological Chemistry · 2011 · 82 citations
    8. Expression of fox-related genes in the skin follicles of Inner Mongolia cashmere goat Asian-Australasian journal of animal sciences · 2017 · 11 citations
    9. Apoptosis in human skin development: Morphogenesis, periderm, and stem cells Developmental dynamics · 1994 · 253 citations
    10. DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control epithelial differentiation Science advances · 2023 · 3 citations
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