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Glossary Terbinafine

antifungal medication treating skin, hair, and nail infections

Terbinafine, commonly known by the brand name Lamisil, is an antifungal medication used to treat fungal infections of the skin, hair, and nails. It works by inhibiting the enzyme squalene epoxidase, which is essential for the synthesis of ergosterol, a key component of fungal cell membranes, thereby leading to the death of the fungal cells.

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Malassezia Species Overgrowth in a Chinchilla Cat

research Malassezia spp. Overgrowth in a Chinchilla Cat

November 2018 in “DergiPark (Istanbul University)”

This case report describes successful treatment of Malassezia overgrowth and resulting dermatitis in a Chinchilla cat using Terbinafine HCL and Omega fatty acid supplements, emphasizing Malassezia's potential as a marker for underlying diseases.

research Determination of the efficacy of terbinafine hydrochloride nail solution in the topical treatment of dermatophytosis in a guinea pig model

51 citations , May 2008 in “Mycoses”

This study found that terbinafine HCl nail solutions with or without DDAIP HCl significantly outperformed ciclopirox nail lacquer in treating guinea pig dermatophytosis, suggesting potential effectiveness for human nail infections.

research Hair loss after terbinafine treatment

3 citations , July 2008 in “British journal of dermatology/British journal of dermatology, Supplement”

Terbinafine can cause hair loss.

research Understanding Microemulsions and Nanoemulsions in (Trans)Dermal Delivery

14 citations , January 2025 in “AAPS PharmSciTech”

This review highlights the promising potential of microemulsions and nanoemulsions in (trans)dermal drug delivery, noting a gap in understanding their distinct mechanisms and composition-related effects on skin permeability, while emphasizing the limited clarity on mesostructures and cosolvent impacts.

Comparison of Rheological Properties, Follicular Penetration, Drug Release, and Permeation Behavior of a Novel Topical Drug Delivery System and a Conventional Cream

research Comparison of rheological properties, follicular penetration, drug release, and permeation behavior of a novel topical drug delivery system and a conventional cream

34 citations , October 2014 in “European journal of pharmaceutics and biopharmaceutics”

This study found that adapalene-loaded solid lipid microparticles may enhance targeted drug delivery into sebum due to their similarity to sebum components, although both this formulation and a standard cream showed equivalent follicular penetration.

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