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This study found that using valproic acid during radiotherapy for glioma was associated with delayed hair loss and improved survival outcomes.

This case report highlights the rare occurrence of life-threatening aplastic anemia in a 65-year-old woman treated with temozolomide for glioblastoma multiforme, emphasizing the need for more frequent blood monitoring to detect severe bone marrow suppression early.

This study found that adding concurrent and adjuvant temozolomide to radiotherapy for patients with anaplastic gliomas improved progression-free survival without adversely affecting health-related quality of life.

This study found that the overexpression of the lncRNA HOTTIP in glioma cells increased resistance to the chemotherapy drug temozolomide, suggesting a key role for miR-10b and EMT processes in this resistance.

The researchers reported that lncRNA HOTTIP plays a crucial role in temozolomide resistance in glioma cells by promoting EMT and miR-10b expression, suggesting it as a potential therapeutic target.