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Some early breast cancer patients have long-term hair loss after chemotherapy, especially older and postmenopausal women.

Chemotherapy often causes skin, nail, and hair side effects, significantly impacting quality of life.

The document concludes that individualized treatment for malignant epithelial tumors is necessary and more research on metastatic squamous cell carcinoma treatments is needed.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

Some breast cancer patients developed permanent hair loss after chemotherapy and hormonal therapy, showing patterns similar to common baldness and alopecia areata.