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research CD4 T cells from mice with alopecia areata express an effector like phenotype and can transfer disease

1 citations , May 2023 in “The Journal of Immunology”

In this animal study, researchers discovered that CD4 T cells from mice with alopecia areata can induce the disease more efficiently than those from unaffected mice, likely by supporting CD8 T cell activation and hair follicle attack.

research Identification of Biomarkers in Affected Hair Follicles from Chronic Discoid LupusErythematosus by Weighted Gene Co-Expression Network Analysis

December 2022 in “Research Square (Research Square)”

In this study, type I interferon response-related genes activated by RIG-1 and IL-17 signaling pathways were significantly up-regulated in both hair follicles and skin tissues affected by chronic discoidal lupus erythematosus.

research Identification of Biomarkers in Affected Hair Follicles from Chronic Discoid Lupus Erythematosus by Weighted Gene Co-Expression Network Analysis

October 2022 in “Research Square (Research Square)”

This study found that type I interferon response-related genes activated by RIG-1 and IL-17 pathways were significantly up-regulated in hair follicle and skin samples with chronic discoidal lupus erythematosus.

research Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1

1 citations , May 2022 in “Frontiers in Pharmacology”

This study found that astilbin downregulates effector CD4+ T cell activities through the CYP1B1/ROS/PPARγ pathway, suggesting its potential use in treating inflammation.

research Regulatory T cell dysfunction and immunotherapeutic breakthroughs in type 1 diabetes

2 citations , January 2026 in “Frontiers in Endocrinology”

This review discusses the impaired functionality of regulatory T cells in the pancreas during the development of Type 1 diabetes, highlighting their role in disease pathogenesis, potential of Treg-based therapies, and challenges in clinical applications.

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community Last Post Before I Switch Back to Finasteride From Dutasteride

in Finasteride/Dutasteride 29 upvotes 1 year ago

The user plans to switch from dutasteride back to finasteride due to worsening hair loss, possibly due to increased scalp testosterone. Others report mixed results with both treatments, showing individual variability.

community Regrowth after 9 months of DHT blockers, and 6 months of HRT

in Transgender 24 upvotes 10 months ago

A 20-year-old saw significant hair regrowth after 9 months of using DHT blockers (finasteride and dutasteride) and 6 months of hormone replacement therapy (HRT) with estradiol. The regrowth is attributed to low testosterone and high estradiol levels, without using Minoxidil.

community Discussion on Finasteride and life.

in Chat 166 upvotes 1 year ago

Finasteride can aid hair regrowth but may cause side effects like depression and sexual dysfunction. Users discuss experiences with finasteride, minoxidil, and RU58841, highlighting varied responses and the importance of informed treatment choices.

community 1.5 years finasterite. 1 tablet daily. Don't see any improvement.

in Is this regrowth? 114 upvotes 11 months ago

The user has been taking finasteride for 1.5 years without seeing improvement in hair regrowth. Suggestions include adding minoxidil or switching to dutasteride, with concerns about side effects.

community Fin & Min Progress, 1.5 Years Fin, 4 Months Min

in Is this regrowth? 7 upvotes 4 months ago

The user experienced hair regrowth using finasteride for 1.5 years and minoxidil foam for 4 months, starting at age 17. They reported no side effects and noted that finasteride helped maintain existing hair while minoxidil contributed to regrowth.

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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