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    GlossarySystemic Medications (Systemic Treatment)

    drugs that affect the entire body via bloodstream

    Systemic medications are drugs that work throughout the entire body rather than targeting a specific area. They are often taken orally or injected, allowing the active ingredients to enter the bloodstream and reach various tissues and organs. This type of treatment is commonly used for conditions that affect multiple parts of the body, such as autoimmune diseases or widespread infections.

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      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 3 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community How much Minoxidil goes systemic?

      in Minoxidil  69 upvotes 4 months ago
      The conversation is about the systemic absorption of Minoxidil and the potential switch from topical to oral Minoxidil due to its effectiveness. The user considers oral Minoxidil after experiencing no side effects from a year of using 15% topical Minoxidil.

      community Does ketoconazole reduce systemic DHT by much?

      in Treatment  6 upvotes 4 months ago
      Ketoconazole shampoo does not significantly reduce systemic or scalp DHT levels and is mainly used for its anti-fungal and anti-inflammatory effects. It is not a replacement for finasteride, which is recommended by some users despite concerns about side effects.

      community Efficacy and Systemic DHT Suppression of Topical Finasteride vs Dutasteride

      in General  122 upvotes 6 months ago
      Topical dutasteride may have limited absorption due to its higher molecular mass compared to finasteride, potentially affecting its efficacy in suppressing DHT locally. Microneedling might enhance dutasteride absorption, possibly offering stronger local DHT suppression with fewer systemic effects.