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      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects

      learn Alfatradiol

      a synthetic estrogen used topically as an anti-androgen

      learn Finasteride

      Frontline, gold standard treatment for combatting androgenic alopecia

      learn Fluridil

      a topical anti-androgen with less systemic involvement

    Research

    5 / 1000+ results
      Androgenetic Alopecia

      research Androgenetic Alopecia

      April 2012 in “Informa Healthcare eBooks”
      AGA is a common hair loss affecting both genders, treated with various therapies to promote regrowth and slow thinning.
      Skin Aging and Menopause: Implications for Treatment

      research Skin Aging and Menopause: Implications for Treatment

      180 citations, January 2003 in “American Journal of Clinical Dermatology”
      Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.
      Estrogens and the Skin

      research Estrogens and the Skin

      137 citations, June 2005 in “Climacteric”
      Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

    Community Join

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      Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

      community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

      in Treatments  450 upvotes 4 months ago
      Topical dutasteride is suggested as a low side-effect treatment for hair loss, with a proposed dose of 0.025% 1ml/day. It is considered better than finasteride due to its even inhibition of DHT isoforms and lower systemic absorption.

      community Estradiol mesotherapy / idea feedback

      in Female  6 upvotes 3 weeks ago
      The conversation discusses using estradiol mesotherapy to replicate hormone replacement therapy results while minimizing systemic exposure. It also covers the use of Spironolactone cream, which reportedly has no systemic side effects, and the potential risks of using bicalutamide and Spironolactone in men.

      community Nandrolone Replacement Therapy

      in Treatment  41 upvotes 1 year ago
      A user discusses starting nandrolone replacement therapy to stop hair loss and improve hair health, noting its benefits over finasteride. They report halted hair loss, improved skin, increased muscle, and a calm mood after three weeks.

      community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI

      in Finasteride/Dutasteride  26 upvotes 4 months ago
      The conversation discusses the effectiveness and skepticism around topical dutasteride for hair loss, with mentions of combining it with other treatments like minoxidil and oral medications. Some users doubt its efficacy due to lack of independent studies and potential conflicts of interest.

      community Progress: 1 year mtf hrt, 9 months Min/Fin

      in Transgender  116 upvotes 3 weeks ago
      The user experienced significant hair regrowth after one year on male-to-female hormone replacement therapy (HRT) and nine months using minoxidil and finasteride. They noted a reduction in body hair and attributed much of the hair regrowth to the addition of minoxidil.