September 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”
This study found that zebrafish and stickleback fish use similar genetic programs for tooth regeneration, despite differences in their dental structures.
This study found that zebrafish and sticklebacks, despite differences in their tooth regeneration structures, share a similar genetic program during tooth regeneration, suggesting a conserved "successionaldentalepithelium" in vertebrates.
5 citations
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January 2015 in “Current Topics in Developmental Biology”
This review discusses the developmental plasticity between teeth and taste buds in cichlid fishes and reports no new experimental findings, highlighting potential implications for craniofacial organ patterning and regeneration.
The researchers observed that in cichlid fishes with different dental structures, tooth replacement accelerated more than three times following tooth extraction, alongside distinct changes in gene expression and cellular interactions over one week, providing insights into tooth regeneration mechanisms in vertebrates.
This study found that loss of Apc due to K14-cre-mediated gene recombination in mice led to aberrant growth in ectodermally derived squamous epithelia, implicating its critical role in specifying epithelial cell fates during embryonic development.