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community After about 3 months of 2mg Estradiol (Sublingual) and 2.5mg Minox (Oral) daily

in Progress Pictures 160 upvotes 10 months ago

A person transitioning is using 2mg sublingual estradiol and 2.5mg oral minoxidil daily for hair regrowth, noting significant progress in three months. They plan to increase estrogen dosage and consider adding dutasteride, discussing the effects and challenges of transitioning.

community 19 months Topical Min/Fin - 7 months HRT

1072 upvotes 3 months ago

The user experienced significant hair regrowth and fullness after starting hormone replacement therapy (HRT) with sublingual estrogen and spironolactone, in addition to using a topical solution of minoxidil, finasteride, ketoconazole, and biotin. They noted initial shedding phases but emphasized that shedding is a sign of future growth.

community Is the combination of spironolactone and estrogen more or less effective than finasteride?

4 upvotes 4 years ago

Spironolactone and estrogen may be more effective for hair regrowth in transgender women than finasteride alone. Estrogen and spironolactone suppress testosterone, potentially reducing DHT more effectively than finasteride.

community My friend is so terrified of balding, he started microdosing estrogen…

in Treatment 1522 upvotes 10 months ago

A person is microdosing estrogen for hair loss after finasteride and dutasteride failed, risking feminizing effects. Alternatives like minoxidil, RU58841, or hair transplants are suggested.

community Well… I Did It. Estrogen Saved My Hairline

in Transgender 732 upvotes 2 years ago

OP transitioned and used Spironolactone, Estradiol Valerate, Minoxidil, and dermarolling, resulting in significant hair regrowth. They advise this method may not be suitable for cis men.

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Research

5 / 504 results

research Iatrogenic androgen and estrogen excess in a postmenopausal woman presenting with facial erythema, acne, and hirsutism

August 2009 in “International Journal of Dermatology”

This case report describes a postmenopausal woman who experienced facial erythema, acne, and hirsutism due to excess androgen and estrogen levels.

research Gender-Affirming Hormone Therapy for Transgender Females

32 citations , September 2018 in “Clinical Obstetrics and Gynecology”

This article states that hormone therapy with estrogens and antiandrogens for transgender females is within an obstetrician-gynecologist's practice scope and involves careful dosing and monitoring to manage short-term thrombotic risks.

research Testosterone therapy for sexual dysfunction in postmenopausal women

46 citations , January 2008 in “Climacteric”

Randomized trials reported that testosterone therapy improved sexual function in postmenopausal women with hypoactive sexual desire disorder, particularly those who had undergone oophorectomy, with reversible and well-tolerated side effects.

research Female pattern hair loss: A comprehensive review

15 citations , July 2020 in “Dermatologic Therapy”

This review discusses the pathophysiology, diagnosis, systemic associations, and treatments for female pattern hair loss and reports no new clinical findings.

research The role of androgens in hormone replacement therapy

6 citations , September 2005 in “Expert Opinion on Pharmacotherapy”

This review discusses the role of androgens in women's sexual health and highlights the need for further research on androgen replacement therapy to optimize quality of life, but reports no new clinical results.

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