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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity
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5 / 1000+ resultsresearch Constitutive Activation of Stat3 Increases Hair Follicle Progenitor Population at the Expense of Bulge Region Keratinocyte Stem Cells
Stat3 activation increases hair follicle progenitors but reduces bulge region stem cells.
research Constitutive Stat3 Activation Alters Behavior of Hair Follicle Stem and Progenitor Cell Populations
Increased Stat3 activity reduces hair follicle stem cells and boosts other stem/progenitor cells.
research Impact of Stat3 Activation Upon Skin Biology: A Dichotomy of Its Role Between Homeostasis and Diseases
Stat3 helps skin heal but can also cause skin diseases if overactive.
research HPV8 E6 Induced STAT3 Activation Leads to Hair Follicle Junctional Zone Keratinocyte Stem Cell Proliferation and Expansion in Actinic Keratoses
HPV8 causes hair follicle stem cells to grow, leading to skin lesions.
research Impact of Stat3 Deletion or Activation on Keratinocyte Stem/Progenitor Cells
Stat3 influences keratinocyte stem cell behavior, affecting differentiation and migration.
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5 / 1000+ resultscommunity PP405: The Ultimate Hair Loss Drug for Complete Hair Growth
PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.
community A stress hormone has been found to signal through skin cells to repress the activation of hair-follicle stem cells in mice
Stress can lead to hair loss by affecting hair-follicle stem cells, and this loss is harder to recover from if one has male pattern baldness (MPB). Treatments like finasteride and minoxidil are used to address hair loss, but stress-related hair loss differs from androgenic alopecia.
community My Theory Regarding a Cause and Cure for Androgenetic Alopecia
Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.
community Creatine is the opposite of minoxidil !
Creatine may counteract minoxidil's hair growth effects by closing potassium ATP channels, potentially leading to hair loss in predisposed individuals. Despite anecdotal reports, there is no conclusive evidence linking creatine to hair loss.
community You will lose hair if your prostaglandins aren't in balance
Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.