Search
for

    Did you mean SRD5A2 gene?
    Glossary SRD5A2 gene

    gene converts testosterone into potent androgen DHT

    The SRD5A2 gene provides instructions for making an enzyme called steroid 5-alpha reductase type 2. This enzyme is crucial for converting testosterone into dihydrotestosterone (DHT), a more potent androgen that plays a key role in the development of male characteristics and is also implicated in conditions like male pattern baldness and certain forms of alopecia.

    Related Terms

    Research 10 of 330

    1. Altered methylation pattern of the SRD5A2 gene in the cerebrospinal fluid of post-finasteride patients: a pilot study Endocrine connections · 2019 · 8 citations
    2. Longer TA repeat but not V89L polymorphisms in the SRD5A2 gene may confer acne risk in the Chinese population Postępy Dermatologii i Alergologii · 2018 · 3 citations
    3. Effects on Steroid 5-Alpha Reductase Gene Expression of Thai Rice Bran Extracts and Molecular Dynamics Study on SRD5A2 Biology · 2021 · 14 citations
    4. Worldwide cohort study of 46, XY differences/disorders of sex development genetic diagnoses: geographic and ethnic differences in variants Frontiers in Genetics · 2024 · 13 citations
    5. Molecular epidemiology of hypospadias: Review of genetic and environmental risk factors Birth Defects Research · 2003 · 103 citations
    6. 5α-Reductase type 2 gene variant associations with prostate cancer risk, circulating hormone levels and androgenetic alopecia International Journal of Cancer · 2006 · 57 citations
    7. Differential expression of steroid 5α-reductase isozymes and association with disease severity and angiogenic genes predict their biological role in prostate cancer Endocrine Related Cancer · 2010 · 30 citations
    8. Rare and common genetic determinants of metabolic individuality and their effects on human health Nature Medicine · 2022 · 29 citations
    9. Identification of a Rare Variant in the <i>SRD5A2</i> Gene in Siblings With 46,XY Disorders of Sexual Development Case Reports in Genetics · 2025
    10. Adjuvant measures and genetic evaluations to improve results of hair transplantation Cellular and Molecular Biology · 2022
    All research results →

    Community 1 of 3

    1. M44 Hairloss Trichotest and Finasteride Reddit · 7 Jun 2023
    All community results →

    Learn

    — no results

    Try a deeper search in learn →