20 citations
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July 2005 in “Experimental dermatology” The fuzzy gene is crucial for controlling hair growth cycles.
3 citations
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May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The unique coat of lykoi cats is likely caused by new variants in the Hairless gene.
11 citations
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February 1989 in “Journal of veterinary medicine. Series A” Crossbreeding certain European cattle breeds may cause hair and physical issues in cattle.
27 citations
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June 2020 in “Genes” The study investigated the genetic basis of the lykoi cat breed's unique sparse hair coat, characterized by hypotrichia and roaning. Whole genome sequencing of a lykoi cat, bred from two independent lineages, revealed two loss of function variants in the Hairless (HR) gene as potential causes. These variants were compared to a dataset of 194 non-lykoi cats, highlighting their uniqueness to the lykoi breed. Further analysis of 14 additional cats from various regions identified four more HR variants, suggesting these genetic differences contributed to the breed's distinct hair phenotype. The findings provided insights into the genetic underpinnings of hypotrichia in cats, specifically linking it to novel HR gene variants.
15 citations
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February 2015 in “Cell & tissue research/Cell and tissue research” P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.