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    GlossarySmoothened Receptor (Smoothened)

    protein involved in Hedgehog signaling pathway for cell growth

    The Smoothened Receptor (SMO) is a protein that plays a crucial role in the Hedgehog signaling pathway, which is important for regulating cell growth and development. When activated, SMO helps transmit signals from the cell surface to the inside of the cell, influencing processes like tissue patterning and stem cell maintenance. Malfunctions in this pathway can lead to developmental disorders and cancers.

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      community Does finasteride/dutasteride reverse aging?

      in Chat  45 upvotes 6 months ago
      Finasteride and dutasteride can improve skin texture and reduce acne by lowering DHT but do not reverse aging. They may enhance skin and hair health for some, but can also cause side effects like dry skin and sexual dysfunction.

      community My way to recovery and advice - Hope this helps (m20)

      in Product  6 upvotes 3 weeks ago
      A 20-year-old shared their experience of reversing hair loss without using minoxidil or finasteride, instead relying on supplements like biotin, collagen, fish oil, saw palmetto, and various vitamins. They emphasized the importance of a balanced supplement schedule and noted improvements in hair health without experiencing additional shedding.

      community Hair Remedies that Don't Work for Anybody Seeking Hair Regrowth

      in Treatment  9 upvotes 4 years ago
      Hair loss treatments discussed include minoxidil, finasteride, and RU58841. Salon products and supplements generally don't work for hair regrowth unless there's a severe nutritional deficiency, while hormonal treatments like estrogen and spironolactone can be effective.

      community One year into a healthier hair routine

      in Progress Pictures  230 upvotes 1 month ago
      The user improved hair health using natural products and plans to start using minoxidil, finasteride, and derma stamping for further hairline improvement. They wash hair weekly with Sweet Ginger shampoo and use Bamboo Charcoal for deep cleansing, while conditioning twice a week.