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This paper discusses the clinical and histological aspects of skin aging, differentiating between endogenous and exogenous factors, and reports no new clinical findings.

This study reported that active smokers, including e-cigarette and hookah users, had worse skin quality with more wrinkles and pigmentation compared to ex-smokers and non-smokers, suggesting smoking negatively impacts skin health and may motivate cessation efforts.

This study found no significant difference in glutathione-S-epoxide transferase activity in hair follicles between smokers and non-smokers, suggesting this enzyme's levels may not indicate polycyclic aromatic hydrocarbon-related cancer risk.

This study found that botulinum toxin type A significantly reduced skin flap necrosis in rats exposed to cigarette smoke, suggesting it may help improve flap viability in smokers.

In this study, patients with diabetic retinopathy and peripheral occlusive arterial disease had significantly longer diabetes duration, higher HbA1c levels, poorer glycemic control, and were more often smokers compared to those without arterial disease, suggesting these factors contribute to disease development.