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Translation-Dependent Skin Hyperplasia Promoted by Type 1/17 Inflammation in Psoriasis

research 1326 Translation-dependent skin hyperplasia is promoted by type 1/17 inflammation in psoriasis

April 2023 in “Journal of Investigative Dermatology”

In this study, researchers found that the protein eIF4E is crucial for keratinocyte proliferation in psoriasis, suggesting it as a potential treatment target for the condition.

research 452 Braicitinib treatment reduced the expansion of CD8+ T cells in C3H mice with skin grafts-induced alopecia areata

October 2023 in “Regular and Young Investigator Award Abstracts”

This study found that Baricitinib significantly reduced hair loss and immune response in a mouse model of alopecia areata.

research Dorsal Skin Reactions of Hairless Dogs to Topical Treatment with Corticosteroids

36 citations , September 1999 in “Toxicologic pathology”

This study suggests that hairless dogs' skin shows sensitivity to topical corticosteroids, highlighting their potential as a model for studying the efficacy and adverse effects of these treatments on skin.

research Post-oncologic skin health: cutaneous recovery and rehabilitation after cancer treatments

March 2026 in “Frontiers in Oncology”

This study concluded that dermatologists are integral to the care of cancer survivors by shifting focus from symptomatic skin treatment to preventive and rehabilitative strategies that enhance long-term skin health and quality of life post-oncology therapy.

research Respective Treatment Modalities with the Use of Combined Ingredients to Address Acne Prone Skin

July 2021 in “Journal of dermatology research and therapy”

This article discusses the mechanisms by which Cutibacterium acnes contributes to acne vulgaris and mentions potential triggers like UV light and tobacco, but it reports no new clinical results.

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Community Join

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community Do you see skin shedding with micro needling?

in Microneedling 6 upvotes 1 year ago

Microneedling can cause skin shedding and inflammation, with some users adjusting needle size or frequency to reduce these effects. Some users combine microneedling with treatments like minoxidil, while others prefer smaller needles or alternative treatments like dutasteride.

community Scalp Inflammation Beyond Psoriasis: A Hidden Player in Hair Thinning

in Technology 54 upvotes 4 months ago

Scalp inflammation may contribute to hair thinning, with treatments like ketoconazole shampoo potentially helping by reducing inflammation. Some users report that DHT blockers and other treatments like finasteride, minoxidil, and RU58841 can alleviate symptoms associated with inflammation.

community Scalp Skin Barrier Health and Hair Follicle Cycling: A Potential Overlooked Connection

in Technology 4 months ago

The conversation discusses the importance of scalp skin barrier health in hair follicle cycling, suggesting treatments like ceramides or niacinamide to support hair growth. It also mentions the use of finasteride for hair loss.

community Inflammation's surprising role in shrinking hair follicles and AGA

in Technology 66 upvotes 4 months ago

Inflammation plays a significant role in hair follicle miniaturization and androgenetic alopecia, with treatments like ketoconazole shampoo, minoxidil, and finasteride being used to address it. Users discuss the benefits of anti-inflammatory treatments and peptides like KPV, alongside traditional hair loss treatments, to improve scalp health and hair quality.

community 8 Months of Treatment with Subpar Results

22 upvotes 4 months ago

The user has been using Dutasteride, Minoxidil, Ketoconazole, and RU58841 for hair loss but sees subpar results. Suggestions include adjusting treatments, considering a hair transplant, and addressing scalp inflammation.

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Learn

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learn Hydrocortisone

a synthetic cortisol used for anti-inflammatory effects

Is hydrocortisone effective for stopping inflammation that blocks hair growth? Sources describe hydrocortisone as a short-course treatment for scalp inflammation such as seborrhoeic dermatitis or eczema, and no verified trial tests it as a hair-regrowth treatment; the corticosteroids used for alopecia areata are the potent prescription ones, and prolonged use of any topical steroid on the scalp risks skin thinning.

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Follistatin

glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

learn Azelaic Acid

acid used for antimicrobial, anti-inflammatory and anti-androgenic properties

learn Sulforaphane

compound from cruciferous vegetables has some mild effects on DHT

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Clinics

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Experts

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35
SMP Specialist
Noelle Skin
Nice, France

Noelle Skin