16 citations
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January 2011 in “Archives of Dermatological Research”
This study identified 77 genes with significant expression changes in expanded human skin, suggesting possible mechanisms for skin regeneration during tissue expansion, including previously unreported genes like HOXA5, HOXB2, and AP1.
11 citations
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February 2019 in “Stem cells international”
In this study, researchers found that while both hair follicles and skin dermis-derived neural crest stem cells are suitable for large-scale manufacturing, skin dermis cells grow faster and are easier to obtain.
11 citations
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August 2013 in “Facial Plastic Surgery Clinics of North America”
This article discusses the use of tissue expansion combined with older surgical techniques to repair large scalp defects and reports no new clinical results.
Can melatonin cause side effects on the skin or hair?No study links melatonin to hair loss; reports are anecdotal. Some users report scalp dryness or irritation from topical products, and a safety review lists mainly mild side effects such as sleepiness and headache.
Can follistatin be applied to the skin, and does any form of it treat hair loss?No study shows that follistatin applied to the skin works, and no form of follistatin is an approved or proven hair-loss treatment. Follistatin injections, "research peptides" and gene therapies sold outside regulated trials are unapproved and of unknown safety.
The conversation discusses whether drinking coffee affects the hair growth benefits of Minoxidil, with one user mentioning that Minoxidil's vasodilation is stronger than caffeine's vasoconstriction, and another sharing personal experience of better hair growth after quitting caffeine while on Minoxidil.
Hair cloning technology is advancing, with clinical trials for improved methods expected by 2028 and 2029, potentially offering a solution for hair loss if donor follicles remain. Organtech's expansion into other biotech areas may secure funding, but the effectiveness of cloning depends on the availability of androgen-resistant donor follicles.
Minoxidil and finasteride aid hair regrowth, but a healthy lifestyle, including proper nutrition and maintaining a healthy weight, enhances their effectiveness. Being underweight can impede hair regrowth, while a balanced diet and addressing deficiencies can improve outcomes.
A peptide-based delivery system for finasteride shows promise in reducing systemic side effects while maintaining hair growth effectiveness. Combining this with other treatments like minoxidil and RU58841 could enhance results with lower systemic absorption.
The conversation discusses the scalp tension theory as a potential factor in hair loss, alongside DHT, inflammation, and other mechanisms. Treatments mentioned include finasteride, minoxidil, and botox injections, with some users exploring additional methods due to varying effectiveness.