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Research

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research A preliminary study of differentially expressed genes in expanded skin and normal skin: implications for adult skin regeneration

16 citations , January 2011 in “Archives of Dermatological Research”

This study identified 77 genes with significant expression changes in expanded human skin, suggesting possible mechanisms for skin regeneration during tissue expansion, including previously unreported genes like HOXA5, HOXB2, and AP1.

research Comparative Analysis of Biological Properties of Large-Scale Expanded Adult Neural Crest-Derived Stem Cells Isolated from Human Hair Follicle and Skin Dermis

11 citations , February 2019 in “Stem cells international”

In this study, researchers found that while both hair follicles and skin dermis-derived neural crest stem cells are suitable for large-scale manufacturing, skin dermis cells grow faster and are easier to obtain.

research Mechanical Stretch Upregulates SDF-1α in Skin Tissue and Induces Migration of Circulating Bone Marrow-Derived Stem Cells into the Expanded Skin

43 citations , December 2013 in “Stem Cells”

Stretching skin increases a certain protein that attracts stem cells, helping skin regeneration.

research Autologus Hair Transplantation Vs Skin Expansion in Management of Cicatricial Alopecia; A Comparative Study

October 2019 in “The Egyptian Journal of Hospital Medicine”

In this study, both hair transplantation and skin expansion were found effective for treating cicatricial alopecia, with transplantation being preferable for adults with smaller areas and skin expansion suited to younger patients with larger areas.

research Scalp Repair Using Tissue Expanders

11 citations , August 2013 in “Facial Plastic Surgery Clinics of North America”

This article discusses the use of tissue expansion combined with older surgical techniques to repair large scalp defects and reports no new clinical results.

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Learn

7 / 33 results

learn Vitamin D

Vitamin made in the skin from sunlight, also taken as a supplement

learn Sulforaphane

Compound found in broccoli sprouts

learn Melatonin

Can melatonin cause side effects on the skin or hair? No study links melatonin to hair loss; reports are anecdotal. Some users report scalp dryness or irritation from topical products, and a safety review lists mainly mild side effects such as sleepiness and headache.

learn Follistatin

Can follistatin be applied to the skin, and does any form of it treat hair loss? No study shows that follistatin applied to the skin works, and no form of follistatin is an approved or proven hair-loss treatment. Follistatin injections, "research peptides" and gene therapies sold outside regulated trials are unapproved and of unknown safety.

learn Hyaluronic Acid

Does hyaluronic acid really hydrate the scalp, or is it mainly for skin care? Hyaluronic acid improved hydration of facial skin in trials. It has not been tested on the scalp.

learn Osteopontin

What does osteopontin do in skin healing and inflammation? Osteopontin takes part in wound repair in mouse skin; its role in human scalp healing and inflammation has not been studied.

learn Scalp Micropigmentation

Does scalp micropigmentation work on all skin tones and hair colors? Providers say SMP pigment can be matched to many skin tones and hair colors; claims that it works on all of them are marketing.

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Community Join

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community Does DHT Cause Complete Baldness?

in Research/Science 4 upvotes 1 year ago

Hair cloning technology is advancing, with clinical trials for improved methods expected by 2028 and 2029, potentially offering a solution for hair loss if donor follicles remain. Organtech's expansion into other biotech areas may secure funding, but the effectiveness of cloning depends on the availability of androgen-resistant donor follicles.

community Targeted Follicular Finasteride Delivery: A Low-Systemic Strategy

15 upvotes 6 months ago

A peptide-based delivery system for finasteride shows promise in reducing systemic side effects while maintaining hair growth effectiveness. Combining this with other treatments like minoxidil and RU58841 could enhance results with lower systemic absorption.

community Exploring all options - Scalp tension theory

14 upvotes 1 year ago

The conversation discusses the scalp tension theory as a potential factor in hair loss, alongside DHT, inflammation, and other mechanisms. Treatments mentioned include finasteride, minoxidil, and botox injections, with some users exploring additional methods due to varying effectiveness.

community CRISPR Is Curing People Right Now. Genetic Hair Loss is Next?

112 upvotes 2 years ago

CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.

community Comprehensive Microneedling Guide

292 upvotes 4 years ago

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

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Clinics

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All 13 clinic results →

Experts

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SMP Specialist
Noelle Skin
Nice, France

Noelle Skin