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Research

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research Glandular metaplasia of hair follicles and other responses to vitamin A excess in cultures of rodent skin

77 citations , April 1968 in “Development”

This study found that excess vitamin A in organotypic cultures of embryonic mouse skin led to abnormal hair follicle development and glandular metaplasia, unlike in untreated controls that showed normal differentiation.

research Reorganization of hair follicles in human skin organ culture induced by cultured human follicle-derived cells

56 citations , July 2005 in “Experimental Dermatology”

This study demonstrated that hair follicle-derived cells can induce hair follicle formation in an in vitro skin organ culture system using human retroauricular skin specimens.

research Organotypic Skin Culture

43 citations , October 2013 in “Journal of Investigative Dermatology”

This article reviews organotypic skin culture systems and their applications in dermatological research, highlighting their ability to model human epidermal conditions in vitro, but it reports no new clinical results.

research The empowering influence of air-liquid interface culture on skin organoid hair follicle development

9 citations , October 2024 in “Burns & Trauma”

This study demonstrates that using transwell culture significantly influences hair follicle formation in skin models, potentially improving dermatology and skin research methodologies.

research Skin Organ Culture: Why?

22 citations , April 1987 in “International Journal of Dermatology”

Skin organ culture helps us understand skin biology and diseases better.

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Clinics

6 / 35 results

All 35 clinic results →

Community Join

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community So does oral minoxidil age your skin or not

43 upvotes 2 years ago

Oral minoxidil may cause dry skin and dark eye bags but doesn't significantly age the skin. Topical minoxidil is toxic to cats, and some users prefer finasteride.

community Minoxidil inhibits lysyl hydroxylase which is needed to produce collagen. If I take 2,5...5 mg of minoxidil every day can I cause my skin to age prematurely?

32 upvotes 1 year ago

Oral minoxidil is effective for hair loss and unlikely to significantly affect collagen synthesis, making it a safe option without causing premature skin aging. Users report positive hair regrowth without noticeable skin aging.

community Neat trick, just turn Jewish to hide crown hair loss

1200 upvotes 4 months ago

The conversation humorously suggests using religious headwear to hide hair loss, mentioning Sikh turbans and Jewish kippahs. It also touches on cultural practices like circumcision and includes various jokes and comments about hair loss solutions.

community If it gets bad enough WE (yes WE) will ALL be getting this

in Styling 302 upvotes 1 year ago

The conversation discusses hair loss and hairstyles for balding men, with some users suggesting treatments like Minoxidil, finasteride, RU58841, and dutasteride. The focus is on embracing unique hairstyles instead of shaving, with mixed opinions on their appeal.

community My kotoconazole shampoo contain this

6 months ago

The conversation discusses the safety and use of ketoconazole shampoo for hair loss, with mentions of zinc pyrithione and selenium sulfide. Users debate the safety of these ingredients, particularly zinc pyrithione, and share opinions on regulatory differences between Europe and the US.

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Learn

9 / 33 results

learn GHK-Cu

What is GHK-Cu and why is it said to be a "miracle" for hair? GHK-Cu is a copper peptide studied mainly for wound healing and skin repair; for hair loss the evidence stops at cell-culture and animal work, and no published human trial has tested it for androgenetic alopecia.
GHK-Cu: Does it have side effects or is it completely safe? For topical cosmetic use, one 24-hour study in cultured skin cells found a low potential for irritation, but no clinical trial has characterised its side effects on the scalp. Injected or oral GHK-Cu has no published human safety data, and the FDA lists injectable GHK-Cu among compounding substances that may present significant safety risks.

learn Dexpanthenol

Provitamin B5, a moisturiser in hair and skin products

learn KY19382

Experimental compound that activates hair-growth signals, tested only in animals

learn Rosemary

Herb whose oil is used in hair care

learn Bimatoprost

Prostaglandin eye drop used for glaucoma and eyelash growth

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Melatonin

Can melatonin cause side effects on the skin or hair? No study links melatonin to hair loss; reports are anecdotal. Some users report scalp dryness or irritation from topical products, and a safety review lists mainly mild side effects such as sleepiness and headache.

learn Follistatin

Can follistatin be applied to the skin, and does any form of it treat hair loss? No study shows that follistatin applied to the skin works, and no form of follistatin is an approved or proven hair-loss treatment. Follistatin injections, "research peptides" and gene therapies sold outside regulated trials are unapproved and of unknown safety.

learn Hyaluronic Acid

Does hyaluronic acid really hydrate the scalp, or is it mainly for skin care? Hyaluronic acid improved hydration of facial skin in trials. It has not been tested on the scalp.

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Experts

1 / 3 results

SMP Specialist
Noelle Skin
Nice, France

Noelle Skin