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research Three‐dimensional adipofascial and dermal structures involved in forehead crease formation

September 2023 in “Clinical anatomy”

This study examined the subcutaneous structures in forehead creases using cadavers and observed that dense fibrous structures connecting the dermis to the frontalis muscle, as well as specific epidermal and dermal characteristics, may contribute to the formation of these creases.

research The riddle of genuine skin microrelief and wrinkles

52 citations , November 2006 in “International Journal of Cosmetic Science”

This review discusses the identification and classification of different wrinkle types based on histological features and microanatomy, emphasizing their varying responses to treatments, and reports no new clinical results.

research The circadian molecular clock creates epidermal stem cell heterogeneity

293 citations , November 2011 in “Nature”

This study found that the circadian clock regulates the activation state of murine epidermal stem cells, affecting tissue homeostasis and susceptibility to tumorigenesis when disrupted.

research On the etiology of vitiligo and gray hair

303 citations , August 1971 in “The American Journal of Medicine”

This report suggests that in vitiligo, melanocytes may be destroyed by the same factors necessary for melanin production, contributing to the skin's depigmentation.

research Two different techniques for frontalis suspension using Gore-Tex to treat severe congenital ptosis

12 citations , February 2017 in “Graefe s Archive for Clinical and Experimental Ophthalmology”

This study compared open and closed surgical techniques for severe congenital ptosis using Gore-Tex slings and found that the closed approach offered better functional outcomes, while the open method provided superior cosmetic results.

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Community Join

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community Claim: Insulin resistance increases the enzyme that creates DHT and affects the liver's ability to control hormones

in Research/Science 4 upvotes 11 months ago

Insulin resistance may increase DHT production, contributing to hair loss, and addressing it through diet, nutrients, and natural DHT blockers like saw palmetto and pumpkin seed oil could help reverse hair loss. Some users prefer medications like finasteride for more effective results.

community So does oral minoxidil age your skin or not

43 upvotes 2 years ago

Oral minoxidil may cause dry skin and dark eye bags but doesn't significantly age the skin. Topical minoxidil is toxic to cats, and some users prefer finasteride.

community Topical Finasteride that doesn’t go systematic is the cure

3 upvotes 1 year ago

Topical finasteride that doesn't penetrate the skin could potentially treat hair loss without side effects. Current challenges include finding a formulation that remains on the scalp without increasing blood levels.

community Remember to take good care of your face too

4 upvotes 8 years ago

Minoxidil can cause facial side effects like puffiness and dryness, but using facial moisturizers, cleansers, and drinking water can help improve skin appearance. Despite hair shedding and quality concerns, the user resumed Minoxidil while maintaining a skincare routine for better facial health.

community Setipiprant/PGE2 feedbacks?

4 upvotes 8 years ago

The conversation discusses using PGE2 as a hair growth stimulant, comparing it to minoxidil, and considering the addition of Setipiprant. Concerns about side effects like skin damage and cost are also mentioned.

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Learn

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learn sh-Polypeptide-7

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Thymosin Beta 4

learn Stem Cell Factor

learn Melatonin

Can melatonin cause side effects on the skin or hair? Melatonin may cause hair loss or thinning in some users, but evidence is limited.

learn Follistatin

Can follistatin be applied to the skin, and does any form of it treat hair loss? No study shows that follistatin applied to the skin works, and no form of follistatin is an approved or proven hair-loss treatment. Follistatin injections, "research peptides" and gene therapies sold outside regulated trials are unapproved and of unknown safety.

learn Scalp Micropigmentation

Does scalp micropigmentation work on all skin tones and hair colors? Scalp micropigmentation can be customized for various skin tones and hair colors.
Is scalp micropigmentation suitable for people with sensitive skin? Providers say scalp micropigmentation suits most skin types and describe patch tests, hypoallergenic pigments and a skin consultation for sensitive skin. These are provider claims rather than independent safety evidence, and pigment reactions remain a risk.

learn retinol

How does retinol improve scalp health and prepare the skin for other hair growth treatments? Retinol improves scalp health by promoting cellular turnover and reducing congestion.

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Experts

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SMP Specialist
Noelle Skin
Nice, France

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Noelle Skin