In this study, a modified Sinclair scale was presented for evaluating hair loss severity in men with female pattern hair loss, outlining stages from normal hair density to severe hair loss while preserving the anterior hairline. Reliability data for using this scale was also included.
6 citations
,
December 2018 in “Australasian Journal of Dermatology”
This study found a strong correlation between the Sinclair Scale and cumulative hair thickness density, allowing the estimation of the Sinclair Scale from trichoscopy-derived statistics.
June 2021 in “Journal of The American Academy of Dermatology”
This correspondence reports that some men with androgenetic alopecia can exhibit hair thinning patterns more typical of females, with variations observed between Australian and Korean populations.
May 2025 in “IP Indian Journal of Clinical and Experimental Dermatology”
This study examined the clinical patterns and trichoscopic features of female pattern hair loss at a rural tertiary care hospital, but it does not report any specific results.
The conversation discusses the potential benefits of sublingual minoxidil for hair loss treatment. It suggests that sublingual minoxidil, which bypasses the liver, may have fewer side effects, greater bioavailability, and could be more effective than oral minoxidil.
Clascoterone won't be available in the US until 2028, with EU filings planned for 2027. It's considered an alternative for those who experience side effects from standard treatments like finasteride and dutasteride.
A 43-year-old experienced gynecomastia after 20 years of taking dutasteride and 7.5mg oral minoxidil. Suggestions include consulting an endocrinologist, checking hormones, and considering Nolvadex or DIM supplements.
PP405 and ABS-201 are promising treatments for male pattern baldness. PP405 shows rapid hair growth in human trials, while ABS-201 shows significant regrowth in animal studies but is still in early human trials.
Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.