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natural substance from Neem tree with medicinal and pesticidal properties
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5 / 801 resultslearn Follistatin
glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin
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learn Microneedling
technique to create small wounds in skin to activate collagen production and hair growth
Research
5 / 1000+ resultsresearch Global behavior of solutions in a chemotaxis model for alopecia areata with signal-dependent sensitivity
This paper examines a chemotaxis model for alopecia areata (AA), focusing on the interactions between CD$ 4^{+} $ T cells, CD$ 8^{+} $ T cells, and interferon-gamma (IFN-$ \gamma $). The study establishes the uniform boundedness and global existence of solutions in one and two dimensions under certain conditions, such as weak signal-dependent sensitivities and high density-dependent death rates. It also explores the globally asymptotic stability and convergence rates of the model's positive equilibrium. The findings suggest that sparse hairless patches can develop and lead to stable AA when specific conditions regarding proliferation rates, death rates, and chemotactic sensitivities are met.
research Global and exponential stabilization of a chemotactic alopecia areata model with signal-dependent diffusion and sensitivity
research How a reaction-diffusion signal can control spinal cord regeneration in axolotls: A modelling study
Axolotls regenerate their spinal cord through a signal that recruits cells, influenced by cell sensitivity and signal spread.
research Exercise activates the PI3K-AKT signal pathway by decreasing the expression of 5α-reductase type 1 in PCOS rats
Exercise improves insulin sensitivity and hormone regulation in PCOS rats.
research An ERK-dependent molecular switch antagonizes fibrosis and promotes regeneration in spiny mice ( Acomys )
High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.
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5 / 253 resultscommunity Verteporfin and Microneedling
Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.
community My Theory Of Androgenic Alopecia
Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.
community If Minoxidil Beards are permanent, why should Finasteride be unable to keep Minoxidil Gains on the scalp?
Whether Finasteride can keep alive the hair gained by Minoxidil after quitting it, and why beard hairs are not as susceptible to miniaturization. It is suggested that scalp hair may be dependent on Minoxidil and that DHT could be countered with Finasteride to some extent, but there is no definitive data proving this.
community Why is dht bad for scalp hair but good for hair on the rest of body?
The conversation discusses why DHT (dihydrotestosterone) negatively affects scalp hair but promotes growth elsewhere on the body. Various opinions include genetic predispositions, differences in hair follicle reactions to DHT, and the potential role of Omega-3 in reducing inflammation and promoting hair health.
community My derm said they came up with a new serum that is better then fin? What’s y’all’s thoughts
A new serum claims to enhance hair regrowth by amplifying oxygen delivery, improving the effectiveness of treatments like exosomes and peptides. Users are skeptical, questioning its efficacy compared to established treatments like Minoxidil and Finasteride.