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      learn Microneedling

      technique to create small wounds in skin to activate collagen production and hair growth

      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

      learn Finasteride

      Frontline, gold standard treatment for combatting androgenic alopecia

      learn GT20029

      research compound made to degrade androgen receptors in scalp

    Research

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      community PP405 Phase 2a press release with early results

      in Research/Science  694 upvotes 9 months ago
      PP405 shows promise in hair regrowth, with 31% of participants experiencing over 20% increase in hair density after 8 weeks. Phase 3 trials are expected in 2026, with potential market availability by 2029-2031.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Don't think I can go on like this anymore

      in Chat  118 upvotes 5 months ago
      A 24-year-old is struggling with severe depression and anxiety due to hair loss, despite using dutasteride and oral minoxidil for two years. They are advised to consider shaving their head, exploring wigs or hair systems, and focusing on other aspects of life like health, relationships, and career.