Prevalence of Metabolic Syndrome and Cardiovascular Risk Factors in Early Onset Male Androgenetic Alopecia: A Cross-Sectional Study in a Tertiary Care Hospital

September 2025 in “ Journal of Medical Sciences and Health ”

J Girishma, A S Sanjana, Rashmi Nagesh, Rajendra Okade, G M Krithika

androgenetic alopecia metabolic syndrome cardiovascular risk blood pressure fasting blood sugar AGA MetS

TLDR Early-onset male hair loss may be linked to higher cardiovascular risk.

This cross-sectional study of 99 male patients aged 18 to 35 with early-onset androgenetic alopecia (AGA) found that 7 patients were diagnosed with metabolic syndrome (MetS), all with mild AGA, and exhibited higher blood pressure and fasting blood sugar levels. The study suggests a potential link between early-onset AGA and increased cardiovascular risk, emphasizing the importance of monitoring metabolic health in AGA patients. It highlights the need for further research with larger sample sizes and advocates for a holistic approach to patient care, involving collaboration between dermatologists and other healthcare providers.

View this study on jmsh.ac.in →

Discuss this study in the Community →

Related Community Posts Join

6 / 1000+ results

community Dutasteride Infertility Debunked: Low T causes true infertility.

in Finasteride/Dutasteride 167 upvotes 5 months ago

Dutasteride and finasteride may temporarily affect semen quality but are unlikely to cause permanent infertility. The Kim et al. study is criticized for poor methodology, and many prefer hair retention over potential fertility concerns, using treatments like dutasteride, finasteride, and minoxidil.

community Everyone is ignoring that plasma finasteride levels are 100x lower with topical compared to oral.

in Research/Science 140 upvotes 1 year ago

Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.

community Being Safe on Oral Minoxidil: tl;dr on the literature.

in Research/Science 53 upvotes 8 months ago

Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 11 months ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Is there a consensus on RU these days? Pyril turned out to be a bust right?

in Research/Science 17 upvotes 1 year ago

The conversation discusses the effectiveness and safety of hair loss treatments, specifically RU58841 and Pyrilutimide (Pyril), with users sharing that Pyril was no more effective than a placebo and expressing concerns about the safety of RU58841 based on personal experiences and the lack of pharmaceutical interest.

Similar Research

5 / 1000+ results

The Association Between Androgenic Alopecia Severity and the Development of Metabolic Syndrome in Saudi Arabia: A Case-Control Study

research The Association Between Androgenic Alopecia Severity and the Development of Metabolic Syndrome in Saudi Arabia: A Case-Control Study

July 2021 in “Journal of Dermatology and Dermatologic Surgery”

There's a significant link between severe hair loss and metabolic syndrome in Saudi Arabia, suggesting early health checks could prevent future issues.

research Circulating and/or Cutaneous Irisin Resistance: A Novel Link Among Androgenetic Alopecia, Comorbid Metabolic Syndrome and Cardiovascular Risks

May 2023 in “Journal of Cosmetic Dermatology”

Androgenetic alopecia is linked to higher cardiovascular and metabolic risks, possibly due to irisin resistance.

research Association of Early-Onset Androgenetic Alopecia and Metabolic Syndrome

5 citations , February 2021 in “JCPSP. Journal of the College of Physicians & Surgeons Pakistan”

Early-onset hair loss in young males is linked to a higher risk of metabolic syndrome.

research Risks for Metabolic Syndrome and Cardiovascular Diseases in Both Male and Female Patients with Androgenetic Alopecia

July 2015 in “Egyptian Journal of Dermatology and Venereology”

People with androgenetic alopecia, both men and women, are more likely to develop heart diseases in the future.

research The Association Between Metabolic Syndrome Components and Hair Loss in Both Male and Female Individuals

2 citations , January 2013 in “Hair therapy & transplantation”

Hair loss may signal metabolic problems and increased risk of heart disease, suggesting people with hair loss should be checked for these issues.