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Research

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research Assessment of Serum Level of Brain-Derived Neurotrophic Factor (BDNF) In Pediatric Alopecia Areata: A Case - Control Study

September 2025

This study found that pediatric alopecia areata patients had significantly lower serum BDNF levels compared to healthy controls, which were associated with greater alopecia severity, higher depressive symptoms, and poorer quality of life.

research Gene polymorphisms and serum levels of BDNF and CRH in vitiligo patients

July 2022 in “PLOS ONE”

In this study, significant associations were observed between specific genetic polymorphisms in BDNF and CRH-R1 and the occurrence of vitiligo, along with differing serum levels of neurotransmitters between vitiligo patients and healthy controls.

research Evaluation of serum brain-derived neurotrophic factor to assess the association between psoriasis and depression

2 citations , September 2015 in “Journal of the Egyptian Women's Dermatologic Society (Print)”

People with psoriasis and depression have lower BDNF levels, which could help measure depression in those with psoriasis.

research Female Pattern Hair Loss and Negative Psychological Impact: Possible Role of Brain-derived Neurotrophic Factor (BDNF)

July 2023 in “Dermatology practical & conceptual”

This study found that women with Female Pattern Hair Loss had lower serum BDNF levels, which correlated with higher stress and depression, suggesting BDNF as a potential marker for psychological impacts in these patients.

research Serum brain‐derived neurotrophic factor and vitamin D: Two concordant players controlling depression among alopecia areata and vitiligo patients: A case–control study

6 citations , March 2023 in “Journal of Cosmetic Dermatology”

In this study, alopecia areata and vitiligo patients had significantly lower serum BDNF and vitamin D levels, which were inversely associated with depression and quality of life, suggesting a potential combined role in the development of depression.

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Community Join

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community Stop Complaining about Creatine. You're just fixated on shedding.

73 upvotes 1 year ago

Creatine is unlikely to cause hair loss as it does not raise DHT levels. Hair loss is more likely due to genetics, medications, or lifestyle changes.

community Is anyone taking creatine while on fin and/or dut?

in Finasteride/Dutasteride 33 upvotes 2 years ago

The conversation discusses the use of creatine while on finasteride and/or dutasteride for hair loss. Opinions vary, with some users reporting no issues and others experiencing accelerated hair loss, suggesting effects are individual.

community Dutasteride Users, do you Still Take Creatine?

10 upvotes 1 year ago

The conversation discusses the potential impact of creatine on hair loss, with some users sharing personal experiences of increased shedding while others argue there's no scientific evidence linking creatine to hair loss. The original poster switched from finasteride to dutasteride and is considering resuming creatine after monitoring its effects on hair loss.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community 1.5 Year - Bad Results (HT, FIN, MINO, PRP, etc)

64 upvotes 2 years ago

A user shared their disappointing results after 1.5 years of hair treatments, including a hair transplant, finasteride, minoxidil, PRP, vegan shampoo, and more. They are considering switching to dutasteride, oral minoxidil, and improving their microneedling routine.

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Learn

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learn Hyaluronic Acid

What’s the difference between using hyaluronic acid as a serum on the scalp versus taking it as a supplement? A serum sits on the scalp surface. Oral hyaluronic acid has small trials on facial wrinkles, none on the scalp or hair.

learn Baicapil

Could a daily serum with Baicapil help revive dormant hair follicles before it’s too late? There is no independent evidence that Baicapil revives dormant follicles; the only human data are the supplier's own unpublished test. A dermatologist can tell whether follicles are still active and which treatments have evidence.

learn Bimatoprost

Can a lash-growth serum like bimatoprost actually work for your scalp? Bimatoprost (Latisse) is FDA-approved only for eyelashes, not the scalp. In the larger of two Allergan phase 2 scalp trials, every bimatoprost formulation gave smaller hair-count gains than minoxidil 5%; the results were posted to ClinicalTrials.gov but never published in a journal, and scalp use remains off-label and experimental.

learn Exosomes

Are exosomes applied as a serum, an injection, or combined with other hair treatments? Clinics offer exosomes as scalp injections, as serums applied after microneedling, or combined with PRP. No exosome product is FDA-approved, and no reliable evidence shows that any of these methods works.

learn Omega 3

Can topical omega-3 oils or serums nourish the scalp, and is taking omega-3 by mouth any better? There is little evidence that omega-3 helps hair, whether taken by mouth or applied to the scalp.

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Clinics

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Hair Loss Treatments
Clínica SerumMérida, Yucatán · MX

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