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This case report describes a patient with secondary syphilis exhibiting distinct dermoscopic features, including moth-eaten alopecia and an erythematous background more pronounced than previously reported.

This review discusses syphilis and reports no new clinical findings; it highlights the need for improved prevention and diagnosis to address increasing infection rates globally and in Hungary.

Syphilis can cause hair loss without other symptoms and should be considered when diagnosing unexplained hair loss.

This case report noted that HIV-infected men who have sex with men are at a higher risk of syphilis, requiring careful staging and prolonged serologic monitoring to assess treatment success.

This case study reports a 26-year-old male with secondary syphilitic alopecia misdiagnosed as alopecia areata, likely contracted through non-penetrative sexual contact. Effective treatment with intramuscular benzathine penicillin G led to complete hair regrowth within three months.