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research Metformin Promotes the Hair-Inductive Activity of Three-Dimensional Aggregates of Epidermal and Dermal Cells Self-Assembled in vitro

5 citations , December 2021 in “Skin Pharmacology and Physiology”

In this study, metformin promoted hair follicle regeneration in vitro by enhancing the hair inductive capability of dermal cells, warranting further exploration for pattern hair loss treatment.

research SELF-ASSEMBLED CHITOSAN NANOPARTICLES FOR PERCUTANEOUS DELIVERY OF CAFFEINE: PREPARATION, CHARACTERIZATION AND IN VITRO RELEASE STUDIES

7 citations , July 2018 in “International Journal of Applied Pharmaceutics”

This study found that optimizing chitosan-tripolyphosphate nanoparticles can enhance the sustained percutaneous delivery of caffeine, with certain conditions affecting stability and release rates.

research Supplementary Material for: Metformin Promotes the Hair-Inductive Activity of Three-Dimensional Aggregates of Epidermal and Dermal Cells Self-Assembled In Vitro

January 2021 in “Figshare”

This study found that metformin may promote hair follicle regeneration by enhancing dermal cell activity in an in vitro mouse model, suggesting potential for treating pattern hair loss.

research Self‐Healing Hydrogel‐Enabled Modular Assembly of Bilayered Skin Construct for Hair Follicle Regeneration

September 2026 in “Advanced Healthcare Materials”

This study demonstrated that a self-healing hydrogel can support in vitro hair follicle-like structures and enhance hair regeneration after implantation, offering a potential approach for personalized hair regeneration therapy.

research Self-Assembly of Solubilized Human Hair Keratins

7 citations , December 2020 in “ACS biomaterials science & engineering”

In this study, researchers demonstrated that human hair keratins can self-assemble into stable nanofibrous networks in vitro, which are compatible with human skin cells and useful for regenerative applications.

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community Surprisingly thorough study on He-Shou-Wu/Fo Ti

13 upvotes 3 years ago

He Shou Wu (Fo Ti) extract was found to prolong the hair growth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.

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