June 2026 in “Clinical and Experimental Dermatology” In this study, researchers observed a rare presentation of alopecia areata characterized by hair shafts with segmental heterochromia and changes in thickness, indicating a fluctuating low-level inflammatory process with recovery periods in the hair's normal characteristics.
16 citations
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November 2003 in “Journal of the American Academy of Dermatology” Iron therapy cured the boy's hair color issue.
18 citations
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April 1989 in “Archives of Dermatology” This study found that segmented heterochromic scalp hair associated with iron-deficiency anemia in a teenage girl completely recovered following iron supplementation, suggesting a role for iron in hair pigment production.
8 citations
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May 2003 in “Clinical and Experimental Dermatology” This case report suggests that nonsynchronized segmented heterochromia in black scalp hair in a 14-year-old girl may represent premature greying unrelated to deficiencies in iron, copper, zinc, or protein.
1 citations
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May 2012 in “Clinical and Experimental Dermatology” This article discusses the presence of iron in segmented heterochromia of scalp hair and concludes that it occurs without iron-deficiency anemia, reporting no new clinical results.