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Glossary Sebaceous Gland Atrophy

shrinkage of oil-producing skin glands

Sebaceous gland atrophy refers to the shrinkage or degeneration of the sebaceous glands, which are small oil-producing glands in the skin. This condition can lead to reduced sebum production, resulting in dry skin and potentially contributing to hair loss, as sebum plays a role in maintaining healthy hair and scalp.

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Research

5 / 1000+ results

research Mycobacterium avium subspecies hominissuis infection in a dog from Germany with multifocal alopecia, exfoliative dermatitis, hypercalcaemia and subsequent sebaceous atrophy

9 citations , January 2015 in “Veterinary record case reports”

This study reports the first successful treatment of a dog infected with Mycobacterium avium subspecies hominissuis using antibiotics, with no zoonotic transmission observed.

research Pharmacological Inhibition of Stearoyl CoA Desaturase in the Skin Induces Atrophy of the Sebaceous Glands

25 citations , February 2013 in “The journal of investigative dermatology/Journal of investigative dermatology”

In this study, topical application of the SCD1 inhibitor XEN103 significantly reduced sebaceous gland size and number in mouse skin, suggesting potential local therapeutic effects for acne treatment without systemic side effects.

research TNF‐inhibitor associated psoriatic alopecia: Diagnostic utility of sebaceous lobule atrophy

20 citations , March 2017 in “Journal of cutaneous pathology”

This study describes tumor necrosis factor inhibitor-associated psoriatic alopecia, highlighting the distinctive histologic feature of sebaceous lobule atrophy, which is potentially reversible and helps differentiate it from idiopathic psoriatic alopecia.

research Sebaceous Gland Atrophy in Psoriasis: An Explanation for Psoriatic Alopecia?

69 citations , June 2016 in “Journal of Investigative Dermatology”

This study found sebaceous gland atrophy and altered gene expression in psoriatic skin lesions, which may relate to the observed hair loss in these areas.

research Adenohypophysitis Associated with Sebaceous Gland Atrophy in a Dog

11 citations , July 1991 in “Veterinary Pathology”

In this case report, a 9-year-old Samoyed dog with a history of dermatitis showed symptoms compatible with chronic sebaceous adenitis, marked by the absence of sebaceous glands and non-granulomatous skin infiltration.

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Community Join

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community Microneedling must reach the stem cells in the upper hair shaft

82 upvotes 4 years ago

Microneedling should target depths of 0.5mm to 1.5mm for hair loss, with weekly sessions at 1mm recommended. Combining microneedling with Minoxidil is common for improved results.

community Hair Loss Inflammation Prevention Stack

48 upvotes 1 year ago

The conversation discusses a hair loss and scalp care routine involving ciclopirox shampoo, benzoyl peroxide, clindamycin gel, clobetasol propionate, and calcipotriol to manage seborrheic dermatitis, folliculitis, and inflammation. It also touches on the role of diet and other treatments like oral minoxidil and pioglitazone for scalp health.

community DHT Harms Scalp Microbiome: DHT Itch is REAL

413 upvotes 1 year ago

Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

community How is dht not beneficial to you?

in Finasteride/Dutasteride 111 upvotes 7 months ago

DHT is important for sexual function and mood, but finasteride and dutasteride can reduce DHT, causing side effects like reduced libido and erectile dysfunction. These treatments are effective for hair loss, but their impact on DHT leads to debate.

community Is this real chat? Finasteride -> fountain of youth and longevity drug?

559 upvotes 1 year ago

Finasteride is discussed as a hair loss treatment with benefits like reduced prostate enlargement and skin aging, but it is not seen as a "fountain of youth." Users report mixed experiences, including side effects like decreased libido and dry eyes.

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