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research Fibromodulin-Deficiency Alters Temporospatial Expression Patterns of Transforming Growth Factor-β Ligands and Receptors during Adult Mouse Skin Wound Healing

32 citations , March 2014 in “PLOS ONE”

This study demonstrates that FMOD deficiency in mice alters TGF-β ligand and receptor expression during wound healing stages, leading to delayed wound closure and increased scar size.

research Wound Healing Mechanisms

October 1982 in “American Journal of Nursing”

Wound healing is a complex process involving different cells and stages, leading to scar tissue formation and strength increase over time.

research Effects of ginsenoside Rb1 on hypertrophic scar remodeling in rabbit model

10 citations , January 2015 in “European journal of pharmacology”

In this animal study, ginsenoside Rb1 demonstrated therapeutic effects on hypertrophic scar remodeling, with the highest efficacy observed at a dose of 0.56 mg.

research Macrophages are necessary for skin regeneration during tissue expansion

44 citations , January 2019 in “Journal of Translational Medicine”

This study found that macrophages are crucial for skin regeneration during tissue expansion, as their depletion in rats led to inhibited skin growth and reduced secretion of key growth factors.

research Immune Cells in Cutaneous Wound Healing: A Review of Functional Data from Animal Models

5 citations , February 2022 in “International Journal of Molecular Sciences”

This review discusses the roles of distinct immune cell types in skin wound healing, highlighting findings from animal studies, but provides no new clinical results.

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Community Join

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community Summary of Procapil video by Haircafe

2 upvotes 1 year ago

Procapil is marketed as a natural hair loss treatment but lacks strong evidence and is industry-biased. Minoxidil and Finasteride are the only FDA-approved treatments for androgenetic alopecia.

community Claim: Insulin resistance increases the enzyme that creates DHT and affects the liver's ability to control hormones

in Research/Science 4 upvotes 11 months ago

Insulin resistance may increase DHT production, contributing to hair loss, and addressing it through diet, nutrients, and natural DHT blockers like saw palmetto and pumpkin seed oil could help reverse hair loss. Some users prefer medications like finasteride for more effective results.

community Happy 4th of July! Verteporfin update.

in Product 64 upvotes 2 years ago

The conversation discusses hair loss treatments, specifically Verteporfin. Users also mention Minoxidil, finasteride, and RU58841.

community Peptides that Stop Hair Loss? | In-depth Literature Review Video

76 upvotes 2 years ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

community Sugar and hairloss

10 upvotes 5 years ago

Cutting sugar may not significantly impact hair loss, as DHT and androgen receptors are the main issues. Effective treatments include finasteride, dutasteride, RU58841, and minoxidil, often combined with microneedling.

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Learn

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learn Hair Transplant

Can a hair transplant cover scars? Clinics say hair transplants can often cover scalp scars, but graft survival in scar tissue is less predictable and needs careful assessment.

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Clinics

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