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HaCaT-Conditioned Medium Supplemented with Small Molecule Inhibitors SB431542 and CHIR99021 and Growth Factor PDGF-AA Prevents the Dedifferentiation of Dermal Papilla Cells In Vitro

research HaCaT-Conditioned Medium Supplemented with Small Molecule Inhibitors SB431542 and CHIR99021 and Growth Factor PDGF-AA Prevents the Dedifferentiation of Dermal Papilla Cells In Vitro

7 citations , March 2021 in “Molecular Medicine Reports”

A mix of specific inhibitors and a growth factor helps keep hair growth cells from losing their properties in the lab.

research Retinoic Acid-Induced Epidermal Transdifferentiation in Skin

1 citations , June 2014 in “Journal of developmental biology”

Retinoic acid helps change skin cells and is important for skin development and hair growth.

research Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia

195 citations , June 2005 in “American Journal of Human Genetics”

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

research Applications of Mesenchymal Stem Cells in Skin Regeneration and Rejuvenation

76 citations , February 2021 in “International Journal of Molecular Sciences”

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

New Developments in Stem Cell Biology and Therapy: Meeting Report from the Working Group of the German Society for Hematology and Oncology

research New Developments in Stem Cell Biology and Therapy: Meeting Report from the Working Group of the German Society for Hematology and Oncology

5 citations , January 2005 in “Cytotherapy”

The meeting highlighted important advances in stem cell research and its potential for creating new medical treatments.

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Community Join

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community Possible topical option for preventing BDNF-related hair loss

in Research/Science 6 upvotes 2 years ago

The conversation discusses hair loss linked to BDNF-increasing nootropics like Semax and Lions Mane. Suggested topical treatments include capsaicin, beta-glucan, and ginseng to counteract TGF-B activation.

community 3.5 month update! (Fin, Min, Microneedling)

in Progress Pictures 321 upvotes 3 years ago

BackToTheFutehair's 3.5 month progress update on their hair loss treatment regimen of finasteride, minoxidil, and microneedling which has led to a significant improvement in thickness and life to the hair. Others have provided encouragement and advice for future treatments.

community 9 months of finasteride - progress??

in Progress Pictures 214 upvotes 10 months ago

The user shared progress pictures after 9 months of using oral finasteride and topical minoxidil for hair loss, noting improvements in hair density. Concerns about side effects of finasteride were discussed, with some users sharing personal experiences.

community anti-androgens help with chronic seborric dermatitis ?! and hence diffuse thinning

in Finasteride/Dutasteride 6 upvotes 1 year ago

An 18-year-old experiencing hair loss and seborrheic dermatitis has tried finasteride, dutasteride, and various shampoos without success. They are considering anti-androgens like RU58841 and KX-826 for oil control and dandruff reduction.

community What happened to topical dutasteride??

in Finasteride/Dutasteride 28 upvotes 1 year ago

Topical dutasteride is considered for hair loss, but concerns about systemic absorption and side effects like reduced libido are common. Users have mixed results, with some preferring oral finasteride or dutasteride despite side effects, while others find topical treatments beneficial but challenging.

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