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research A new hair follicle-derived human epidermal model for the evaluation of sunscreen genoprotection

27 citations , June 2015 in “Journal of photochemistry and photobiology. B, Biology”

This study reported that sunscreen with SPF50+ provides a high level of DNA protection against UV-induced damage in a reconstituted human epidermis model, comparable to that in skin explants.

research LB788 Development of a novel three-dimensional human epidermal model from plucked hair follicle-derived keratinocytes

July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study concluded that a new model of reconstructed human epidermis using keratinocytes from plucked hair follicles offers a less-invasive alternative to conventional skin-derived models for skin research.

research 138 Characterization of xenobiotic metabolizing enzymes of a reconstructed human epidermal model from adult hair follicles

September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

In this study, the reconstructed skin epidermal model derived from hair follicles showed gene expression and enzyme functionality consistent with native human skin, suggesting its viability for studying skin metabolism and potential toxicity of dermo-cosmetic ingredients.

research Establishment of a new three‐dimensional human epidermal model reconstructed from plucked hair follicle‐derived keratinocytes

12 citations , May 2016 in “Experimental Dermatology”

The researchers concluded that their new reconstructed human epidermis model from plucked hair follicle-derived keratinocytes offers a safer and simpler alternative to traditional skin-derived models for studying epidermal function.

research Expression of type 1 5α-reductase and metabolism of testosterone in reconstructed human epidermis (SkinEthic®): a new model for screening skin-targeted androgen modulators

3 citations , December 2000 in “International Journal of Cosmetic Science”

This study established that a human epidermal model can be utilized to assess 5alpha-reductase activity and evaluate enzyme modulators, such as finasteride, for dermatological applications.

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community If you gentlemen are balding like myself, I encourage you to try shaving.

in Shaved/buzzed 1608 upvotes 1 year ago

A user encouraged others experiencing hair loss to try shaving their heads, sharing their own positive experience despite briefly using finasteride and natural methods. Responses were mixed, with some supporting the decision and others suggesting treatments like minoxidil and finasteride, while many commented on the appearance changes.

community Temporalis Hypertrophy and hair loss

in Treatment 24 upvotes 1 year ago

Hair loss treatments include finasteride, minoxidil, and scalp exercises. Opinions vary on the effectiveness, with some attributing hair loss to muscle tension and inflammation, while others focus on genetics and DHT.

community Why is Finasteride seen as “scary” for men, but hormonal birth control is totally normalized for women?

in Finasteride/Dutasteride 757 upvotes 1 year ago

Finasteride is seen as risky for men due to side effects like erectile dysfunction, while hormonal birth control for women is normalized despite its side effects. The discussion points out a double standard influenced by societal and gender norms.

community Last Post Before I Switch Back to Finasteride From Dutasteride

in Finasteride/Dutasteride 29 upvotes 1 year ago

The user plans to switch from dutasteride back to finasteride due to worsening hair loss, possibly due to increased scalp testosterone. Others report mixed results with both treatments, showing individual variability.

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