41 citations
,
January 2007 in “Journal of Korean Medical Science”
This study found that combining minoxidil with all-trans retinoicacid additively promoted hair growth in vitro by activating certain cell survival pathways and reducing apoptosis markers more effectively than minoxidil alone.
28 citations
,
August 1981 in “Journal of the American Academy of Dermatology”
This article discusses the urgent issue of preserving freedom of choice in dermatology, highlighted by the American Academy of Dermatology, and reports no new research findings.
20 citations
,
April 2019 in “BioMed Research International”
This study found that DNA hypermethylation was present in melasma lesions, and treatments with sunscreen, niacinamide, and retinoicacid were associated with decreased methylation and clinical improvement.
This article reviews different generations of synthetic retinoids for dermatological use, discussing their efficacy and significant side effects, but reports no new clinical results.
April 2016 in “Journal of Investigative Dermatology”
This study found that both topical tretinoin and oral isotretinoin altered the free fatty acid profile of sebum in acne patients, affecting bacterial growth differently for S. epidermidis and S. aureus.
Minoxidil is more effective when combined with retinoicacid, such as tretinoin or tazarotene, enhancing hair growth. Some users experience significant regrowth, while others see minimal effects or side effects.
Topical minoxidil with retinoicacid is effective but causes scalp irritation, leading the user to consider switching to 2.5mg oral minoxidil. Oral minoxidil may cause body hair growth and heart-related side effects, so it's advised to use it under medical guidance.
Using a topical formula with 5% minoxidil and 0.01% retinoicacid is considered effective, as tretinoin can enhance minoxidil results and improve scalp health.
The solution contains minoxidil, finasteride, azelaic acid, caffeine, retinoicacid, and procapil. Users suggest minoxidil with tretinoin and a 5-alpha reductase inhibitor, while dismissing retinoic and azelaic acids as unnecessary.
A 19-year-old male has been experiencing aggressive hair loss since age 15/16 and has tried various treatments including topical Minoxidil, microneedling, tretinoin, retinoicacid, stemoxydine, RU58841, and finasteride without success. He recently added oral Minoxidil but continues to experience significant hair thinning and is considering switching to dutasteride.