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Research

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research Expanding the Clinical and Mutational Spectrum of Recessive AEBP1-Related Classical-Like Ehlers-Danlos Syndrome

20 citations , February 2019 in “Genes”

This study identifies a likely pathogenic homozygous missense variant in the AEBP1 gene in a patient with symptoms of classical Ehlers-Danlos syndrome, suggesting new perspectives for EDS classification and research.

research Recessive Epidermolysis Bullosa Simplex Phenotype Reproduced in Vitro

20 citations , November 2003 in “American Journal Of Pathology”

Fibroblasts from healthy donors can prevent changes seen in recessive epidermolysis bullosa simplex.

research No Evidence That Human Papillomavirus Is Responsible for the Aggressive Nature of Recessive Dystrophic Epidermolysis Bullosa–Associated Squamous Cell Carcinoma

14 citations , August 2010 in “Journal of Investigative Dermatology”

HPV does not cause aggressive cancer in RDEB patients.

research Recessive Mutation in FAM83G Associated with Palmoplantar Keratoderma and Exuberant Scalp Hair

10 citations , November 2017 in “Journal of Investigative Dermatology”

In this study, researchers identified a novel homozygous variant in the FAM83G gene responsible for autosomal recessively inherited palmoplantar keratoderma with curly hair in a consanguineous Pakistani family, suggesting FAM83G plays a crucial role in skin and hair homeostasis.

research Substrate specific sulfatase activity from hair follicles in recessive X-linked ichthyosis

8 citations , September 1987 in “Acta Dermato Venereologica”

In this study, the researchers used structural studies and molecular calculations to suggest that the enzyme in RXLI patient hair follicles is less efficient, rather than completely inactive.

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Community Join

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community Doctor rates celebrity hair transplants

685 upvotes 6 months ago

Celebrities often use hairpieces, transplants, or medications like Minoxidil to maintain their hairlines. Hair transplants require ongoing medication, and opinions on their success vary.

community Temple recession continues, 19 MtF, Monotherapy w/ confirmed low T, also taking 1.25mg Finasteride,

in Transgender 115 upvotes 11 months ago

A 19-year-old transgender individual is experiencing worsening temple recession despite taking female hormones and 1.25mg finasteride. They are seeking advice on additional treatments to address hair loss.

community Water retention from topical minoxidil

4 upvotes 4 years ago

Topical minoxidil can cause water retention, making the face appear swollen. Switching from liquid to foam and reducing application frequency may help; using dandelion root extract as a diuretic is also suggested.

community Thining and hairline recession

4 upvotes 3 weeks ago

A 23-year-old male has been experiencing hair loss for four years and has tried various treatments like finasteride, topical dutasteride, and kx-826, but experienced side effects. He switched from topical to oral minoxidil and is seeking advice on future therapies, with suggestions including seeing a dermatologist, microneedling, and considering RU58841 despite potential side effects.

community Having really noticeable hair recession and thinning after getting good results on fin 1mg for almost 8 months.

5 upvotes 1 month ago

A user experienced hair thinning and recession after initially seeing positive results with finasteride 1mg for almost 8 months. They suspect their significant weight loss and potential nutrient deficiencies might be contributing factors and are considering adding minoxidil or switching to dutasteride.

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Learn

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learn Hair Transplant

What is the graft survival rate in hair transplants? Many clinics quote graft survival of 90% to 95%, but independent data are limited and results vary with the surgeon, the technique and the patient.
How can I measure the results of a hair transplant? Clinics judge transplant results mainly by hair density counts and appearance; there is no single standard measure, and the success figures clinics quote are self-reported.
What is the success rate of hair transplants? Clinics report high graft survival, but there is no independent overall success rate and results vary.

learn Scalp Micropigmentation

How long does Scalp Micropigmentation last, and does it need touch-ups over time? Providers say SMP usually needs a touch-up every 1 to 5 years. It fades but does not fully disappear, and removal needs laser treatment that may be incomplete.

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