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Hair and nail cells share similar proteins, indicating a common differentiation pathway.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Women with the NIH type of PCOS have more obesity and higher risk of diabetes and heart disease than those with other types of PCOS.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.