In this study, preconditioning hair follicle-derived stem cells with valproic acid and/or rapamycin was shown to protect against damage caused by oxygen glucose and serum deprivation, potentially enhancing stem cell therapy efficacy for ischemic stroke by improving cell adaptation to oxidative stress.
7 citations
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October 1992 in “PubMed” This study investigated peptidergic nerve fibers in sinus hair follicles of various mammals and found that CGRP fibers were more densely distributed than SP fibers across different regions of the follicles.
In this case report, an 11-year-old girl with dissecting cellulitis of the scalp showed an excellent response to oral isotretinoin after other treatments failed, highlighting the treatment challenges and need for awareness in managing this rare condition.
16 citations
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March 2025 in “International Journal of Molecular Sciences” This review analyzed 12 clinical studies on extracellular vesicle therapies, finding potential benefits for skin aging, acne scars, alopecia, and wound healing, but highlighted significant challenges like production standardization and lack of large-scale studies.
24 citations
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August 2007 in “Journal of pediatric surgery” This report of two pediatric cases suggests that careful diagnosis of scalp lesions as possible dermatophytic infections is crucial to avoid inappropriate surgical treatment and facilitate proper conservative management.
2 citations
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October 1931 in “Archives of Dermatology and Syphilology” This report describes a rare case of scalp kerion due to microsporosis in a Portuguese child, noting the unusual combination with other microsporid features and treatment details.
5 citations
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July 2022 in “Orphanet journal of rare diseases” This study found that RSPO1 mutations in patients with a 46XX disorder of sexual development contribute to impaired skin integrity and increased risk of squamous cell carcinoma in areas subject to friction.
April 2024 in “Archives of Dermatological Research” This research review explores an algorithmic approach to scalp reconstruction, emphasizing the importance of considering defect location, size, and local scalp anatomy in optimizing cosmetic and functional surgical outcomes.
1 citations
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January 2020 in “Journal of Crohn's and colitis” In this case series, researchers observed that patients with inflammatory bowel disease often experienced vitamin C deficiency, which was linked to symptoms of scurvy, highlighting the need for dietary counseling.
418 citations
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September 2012 in “Nature” This study reports the first instance of skin autotomy in mammals, specifically in African spiny mice, and suggests they may possess a greater regenerative capacity than previously understood, possibly offering insights for regenerative medicine.