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    Glossary Vitamin D

    fat-soluble vitamin essential for calcium absorption and bone health

    Vitamin D is a fat-soluble vitamin that is crucial for maintaining healthy bones and teeth by aiding in the absorption of calcium and phosphorus from the gut. It can be obtained through exposure to sunlight, certain foods, and supplements. There are two main forms: vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol), with D3 being more effective at raising blood levels of the vitamin. Deficiency in vitamin D can lead to conditions such as rickets in children and osteomalacia in adults.

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    1. Vitamin D: More Than a “Bone-a-Fide” Hormone Molecular endocrinology · 2003 · 276 citations
    2. Vitamin D metabolism and function in the skin Molecular and cellular endocrinology · 2011 · 185 citations
    3. Genetic Disorders and Defects in Vitamin D Action Endocrinology and metabolism clinics of North America · 2010 · 151 citations
    4. Inactivation of the Vitamin D Receptor Enhances Susceptibility of Murine Skin to UV-Induced Tumorigenesis 2008 · 148 citations
    5. Vitamin D and the skin: Focus on a complex relationship: A review Journal of Advanced Research · 2014 · 139 citations
    6. The Vitamin D Receptor Is a Wnt Effector that Controls Hair Follicle Differentiation and Specifies Tumor Type in Adult Epidermis PloS one · 2008 · 127 citations
    7. Extraskeletal actions of vitamin D Annals of the New York Academy of Sciences · 2016 · 119 citations
    8. Mutations in the vitamin D receptor and hereditary vitamin D-resistant rickets BoneKEy Reports · 2014 · 107 citations
    9. Overexpression of Hedgehog Signaling Is Associated with Epidermal Tumor Formation in Vitamin D Receptor–Null Mice Journal of Investigative Dermatology · 2011 · 100 citations
    10. Does D matter? The role of vitamin D in hair disorders and hair follicle cycling Dermatology Online Journal · 2010 · 98 citations
    11. Vitamin D-dependent rickets type II. Defective induction of 25-hydroxyvitamin D3-24-hydroxylase by 1,25-dihydroxyvitamin D3 in cultured skin fibroblasts. Journal of Clinical Investigation · 1985 · 81 citations
    12. Hairless Suppresses Vitamin D Receptor Transactivation in Human Keratinocytes Endocrinology · 2005 · 78 citations
    13. Vitamin D and the skin Journal of bone and mineral metabolism · 2010 · 76 citations
    14. Topographical and developmental studies on target sites of 1,25 (OH2) vitamin D3 in skin 1984 · 70 citations
    15. Quantification of the Vitamin D Receptor−Coregulator Interaction Biochemistry · 2009 · 62 citations
    16. Vitamin D and androgen receptor-targeted therapy for triple-negative breast cancer Breast Cancer Research and Treatment · 2016 · 59 citations
    17. The Vitamin D Receptor as Tumor Suppressor in Skin Advances in experimental medicine and biology · 2020 · 55 citations
    18. Vitamin D Receptor, UVR, and Skin Cancer: A Potential Protective Mechanism Journal of Investigative Dermatology · 2008 · 51 citations
    19. Vitamin D and skin diseases: A review Indian Journal of Dermatology, Venereology and Leprology · 2015 · 48 citations
    20. 'Atrophic telogen effluvium' from cytotoxic drugs and a randomized controlled trial to investigate the possible protective effect of pretreatment with a topical vitamin D3 analogue in humans British Journal of Dermatology · 2005 · 47 citations
    21. Modulatory role of vitamins A, B3, C, D, and E on skin health, immunity, microbiome, and diseases Pharmacological Reports · 2023 · 47 citations
    22. Vitamin D resistance 2006 · 45 citations
    23. The vitamin D receptor functions as a transcription regulator in the absence of 1,25-dihydroxyvitamin D3 The Journal of Steroid Biochemistry and Molecular Biology · 2015 · 37 citations
    24. Mechanisms Involved in the Relationship between Vitamin D and Insulin Resistance: Impact on Clinical Practice Nutrients · 2021 · 37 citations
    25. Evidence for 1,25-Dihydroxyvitamin D3-independent Transactivation by the Vitamin D Receptor 2007 · 36 citations
    26. Hairless Modulates Ligand-Dependent Activation of the Vitamin D Receptor-Retinoid X Receptor Heterodimer Biological & pharmaceutical bulletin · 2012 · 28 citations
    27. Serum vitamin D3 level in patients with female pattern hair loss International Journal of Trichology · 2016 · 23 citations
    28. The Molecular Biology of the Vitamin D Receptor Humana Press eBooks · 2010 · 22 citations
    29. The Transient Role for Calcium and Vitamin D during the Developmental Hair Follicle Cycle Journal of Investigative Dermatology · 2016 · 18 citations
    30. Vitamin D increases expression of cathelicidin in cultured sebocytes Archives of Dermatological Research · 2012 · 18 citations