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    Glossary Vitamin D3 analogue

    synthetic compound mimicking natural Vitamin D3's biological effects

    A Vitamin D3 analogue is a synthetic compound designed to mimic the biological effects of natural Vitamin D3. These analogues are often used in medical treatments to regulate calcium and phosphate metabolism, and they can be particularly useful in managing conditions like psoriasis and certain types of alopecia, where they help modulate immune responses and promote skin health.

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    1. Topically active vitamin D3 analogue, 1α,24-dihydroxy-cholecalciferol, has an anti-proliferative effect on the epidermis of guinea pig skin 1987 · 16 citations
    2. 'Atrophic telogen effluvium' from cytotoxic drugs and a randomized controlled trial to investigate the possible protective effect of pretreatment with a topical vitamin D3 analogue in humans British Journal of Dermatology · 2005 · 47 citations
    3. Effects of 1?,25-dihydroxy-vitamin D3 and calcipotriol on organotypic cultures of outer root sheath cells: a potential model to evaluate antipsoriatic drugs Archives of dermatological research · 1993 · 10 citations
    4. Vitamin D<sub>3</sub> metabolites and analogues in the treatment of scalp psoriasis Journal of dermatological treatment · 1998 · 5 citations
    5. Deficiency in alopecia areata and responsiveness to vitamin D analogues: A prospective trial Journal of Pakistan Association of Dermatologists · 2023
    6. Vitamin D and alopecia areata: possible roles in pathogenesis and potential implications for therapy. PubMed · 2019 · 14 citations
    7. Proliferation and Differentiation of Cultured Human Keratinocytes is Modulated by 1,25(OH)<sub>2</sub>D<sub>3</sub> and Synthetic Vitamin D<sub>3</sub> Analogues in a Cell Density‐, Calcium‐ and Serum‐Dependent Manner* Pharmacology & toxicology · 1997 · 39 citations
    8. Analysis of 1,25-Dihydroxyvitamin D3 Receptors (VDR. in Basal Cell Carcinomas ˜The œAmerican journal of pathology · 1999 · 42 citations
    9. The Vitamin D Receptor Is a Wnt Effector that Controls Hair Follicle Differentiation and Specifies Tumor Type in Adult Epidermis PloS one · 2008 · 127 citations
    10. Psoriasis of the Scalp American Journal of Clinical Dermatology · 2001 · 128 citations
    11. Psoriasis treatment in difficult locations: scalp, nails, and intertriginous areas Clinics in Dermatology · 2008 · 104 citations
    12. Clinical application of 5α-reductase inhibitors Journal of endocrinological investigation · 2001 · 46 citations
    13. TGF‐β<sub>2</sub> is specifically expressed in human dermal papilla cells and modulates hair folliculogenesis Journal of Cellular and Molecular Medicine · 2009 · 43 citations
    14. Calcipotriene/betamethasone in the treatment of psoriasis: a review article Expert opinion on pharmacotherapy · 2009 · 24 citations
    15. ADVANCES IN PSORIASIS THERAPY Dermatologic Clinics · 2000 · 20 citations
    16. Successful Treatment of Lichen Spinulosus with Topical Tacalcitol Cream Pediatric dermatology · 2010 · 11 citations
    17. From molecular biology to therapeutics 1994 · 7 citations
    18. An Update on Scalp Psoriasis Actas Dermo-Sifiliográficas · 2009 · 2 citations
    19. Clinical Manifestation and Classification of Japanese patients with Inherited Keratinizing Disorders 2012 · 1 citations
    20. 9. Immunology and Genetics Medical & surgical dermatology · 2009
    21. Research Snippets British Journal of Dermatology · 2005
    22. Medical Therapies Springer eBooks · 2019
    23. Murgi: un antiguo puerto romano: un antiguo puerto romano Revista de arqueología · 1995
    24. The skin as an endocrine organ Dermato-endocrinology · 2009 · 75 citations
    25. Dermatologic therapy: December 1987 to December 1988 Journal of The American Academy of Dermatology · 1990
    26. Vitamin D and the skin: Focus on a complex relationship: A review Journal of Advanced Research · 2014 · 139 citations
    27. Extraskeletal actions of vitamin D Annals of the New York Academy of Sciences · 2016 · 119 citations
    28. Differential activity of 2-methylene-19-nor vitamin D analogs on growth factor gene expression in rhino mouse skin and comparison to all-trans retinoic acid PloS one · 2017 · 2 citations
    29. Vitamin D metabolism and function in the skin Molecular and cellular endocrinology · 2011 · 185 citations
    30. Vitamin D and androgen receptor-targeted therapy for triple-negative breast cancer Breast Cancer Research and Treatment · 2016 · 59 citations