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This review discusses the potential role of vitamin D deficiency in cardiovascular and renal diseases and suggests that supplemental vitamin D could benefit cardiovascular outcomes, especially in African American and postmenopausal women; it reports no new clinical findings.

This study found that 2MbisP increases epidermal thickening more rapidly than atRA in rhino mice, while both compounds similarly reduce utricle size.

This study suggests that while vitamin D3 deficiency is linked to alopecia areata severity, evidence for the effectiveness of supplementation or topical calcipotriol treatment remains inconsistent and low quality.

Vitamin D is crucial for skin health and managing skin diseases.

This research highlights that engineered mice lacking the vitamin D receptor show multiple health issues similar to human vitamin D deficiency, underscoring the widespread impacts of the vitamin D endocrine system.

This review discusses the regulation and function of vitamin D and its receptor in skin cells, highlighting their roles in processes such as proliferation inhibition, differentiation, and innate immunity, but reports no new results.

This review examines the functions of vitamin D and its receptor in skin and explores how these are regulated, reporting no new clinical results.

This study found that AR/VDR-targeted agonist hormone therapy can inhibit cell viability in HR2-av triple-negative breast cancer cell lines through multiple mechanisms and may enhance the effects of chemotherapy.

This study suggests that analyzing hair samples with a liquid chromatography-mass spectrometric assay may offer a reliable method to measure average quarterly vitamin D levels, potentially complementing blood tests.

This study found that vitamin D regulates cholesterol metabolism and may influence prostate cancer development through mechanisms affecting prostate cell growth and sex hormone metabolism.

This review highlights that vitamin D is increasingly recognized for its roles in skin health, including treatment of psoriasis, potential applications in conditions like atopic dermatitis, and possible prevention of skin malignancies, as observed in various studies linking low levels to autoimmune skin diseases.

In this study, the analysis of Ukraine's pharmaceutical market from 2020 to 2023 found a large variety of Vitamin D3 preparations, predominantly domestic and synthetic, with capsule forms being common; consumer surveys highlighted that doctor recommendations strongly influenced purchasing decisions.

This study observed that 25-hydroxyvitamin D3 restored rickets symptoms in genetically modified rats, suggesting its direct action through vitamin D receptor pathways.

In this study, topical calcipotriol was found to be more effective than oral vitamin D for improving mild to moderate alopecia areata, with a 68% improvement rate and no correlation between serum vitamin D levels and treatment efficacy.

This study found that microneedling combined with either topical vitamin D3 or bimatoprost was more effective for hair regrowth in localized alopecia areata than microneedling alone, though differences between the two additives disappeared after three months.

This review discusses the role of vitamin D metabolism in skin immunity and wound healing but does not present new results, highlighting the need for further research into its therapeutic applications.

This review explores the diverse physiological roles of the vitamin D endocrine system, discussing current research on receptor structure, transcription details, murine models, and alternative receptors, but reports no new findings.

This review discusses the multifaceted role of vitamin D in the body, noting its influence on calcium balance, hair cycle maintenance, cell proliferation, cardiovascular function, and immune modulation, with no new clinical results reported.

In this study, synthetic vitamin D3 analogs stimulated hair growth and formation of normal hair follicles in nude mice, unlike the natural form 1,25 dihydroxyvitamin D3.

This review discusses the relationship between vitamin D and various skin diseases, highlighting recent findings on its role and the importance of assessing and correcting vitamin D levels, but reports no new clinical results.

The testes significantly contribute to vitamin D metabolism and may affect male reproductive health and conditions like hair loss.

This study found that both the natural ligand 1alpha,25(OH)(2)D(3) and the synthetic agonist LG190178 bind similarly to the vitamin D receptor's coregulator motifs, suggesting similar biological functions.

This article outlines the potential for upregulating the vitamin D receptor in treating hair disorders, emphasizing the need for further studies to evaluate vitamin D's role in the hair cycle.

This review discusses the various roles of vitamin D in skin disorders, including established use in psoriasis and potential applications for atopic dermatitis and skin cancer prevention, but reports no new clinical results.

In this study, VD(3) pretreatment increased hair follicle formation in a rat model by promoting dermal papilla cell differentiation, suggesting potential for hair regeneration therapy.

This chapter discusses the molecular biology of the vitamin D receptor in gene transcription and reports no new results; it highlights recent findings on receptor activity independent of its usual ligand.

In this study, OCT showed strong nuclear binding in certain skin cells, suggesting similar genomic effects to vitamin D with potential therapeutic benefits due to its lower calcaemic effect.

This study confirmed that 25(OH)D3 can be detected in hair samples from healthy young adults, but no correlation was found between hair and serum 25(OH)D3 concentrations, indicating limited potential as a standalone biomarker.

This review reports that vitamin D plays an important role in hair follicle development, with a negative correlation observed between serum vitamin D levels and female pattern hair loss, suggesting further research is needed before recommending vitamin D as a treatment.