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    Glossary Vitamin D Receptor

    protein that binds vitamin D to regulate gene expression

    The Vitamin D Receptor (VDR) is a protein found in various cells throughout the body that binds to vitamin D, allowing it to regulate the expression of specific genes. This receptor plays a crucial role in maintaining calcium and phosphate balance, which is essential for healthy bone formation, and it also influences immune system function and hair follicle cycling.

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    Research 30 of 1000+

    1. Lentinula edodes (Shiitake) extract as a vitamin D receptor activator to enhance skin adaptogenic responses Scientific Reports · 2026
    2. Hairless Modulates Ligand-Dependent Activation of the Vitamin D Receptor-Retinoid X Receptor Heterodimer Biological & pharmaceutical bulletin · 2012 · 28 citations
    3. Vitamin D activates type A natriuretic peptide receptor gene transcription in inner medullary collecting duct cells Kidney international · 2007 · 17 citations
    4. The Vitamin D Receptor Is Required for Activation of cWnt and Hedgehog Signaling in Keratinocytes Molecular Endocrinology · 2014 · 56 citations
    5. Stress-induced c-Jun-dependent Vitamin D Receptor (VDR) Activation Dissects the Non-classical VDR Pathway from the Classical VDR Activity 2007 · 31 citations
    6. Ligand-Dependent Actions of the Vitamin D Receptor Are Required for Activation of TGF-β Signaling during the Inflammatory Response to Cutaneous Injury Endocrinology · 2012 · 56 citations
    7. Vitamin D receptor cross-talk with p63 signaling promotes epidermal cell fate 2023 · 1 citations
    8. Physical and Functional Interaction between the Vitamin D Receptor and Hairless Corepressor, Two Proteins Required for Hair Cycling Journal of Biological Chemistry · 2003 · 215 citations
    9. Ligand-Independent Actions of the Vitamin D Receptor Maintain Hair Follicle Homeostasis Molecular Endocrinology · 2004 · 144 citations
    10. Evidence for 1,25-Dihydroxyvitamin D3-independent Transactivation by the Vitamin D Receptor 2007 · 36 citations
    11. 698 Effect of lithocholic acid as a ligand of vitamin D receptor on hair growth in alopecia Journal of Investigative Dermatology · 2016
    12. Effect of a transcriptional inactive or absent vitamin D receptor on beta-cell function and glucose homeostasis in mice 2016 · 13 citations
    13. Tryptophan Missense Mutation in the Ligand‐Binding Domain of the Vitamin D Receptor Causes Severe Resistance to 1,25‐Dihydroxyvitamin D Journal of Bone and Mineral Research · 2002 · 47 citations
    14. Role of the vitamin D receptor in hair follicle biology The Journal of Steroid Biochemistry and Molecular Biology · 2007 · 54 citations
    15. Mutations in the vitamin D receptor gene in four patients with hereditary 1,25-dihydroxyvitamin D-resistant rickets Arquivos Brasileiros de Endocrinologia & Metabologia · 2008 · 24 citations
    16. The role of nuclear hormone receptors in cutaneous wound repair Cell Biochemistry and Function · 2014 · 68 citations
    17. Role of vitamin D and calcium signaling in epidermal wound healing Journal of endocrinological investigation · 2022 · 15 citations
    18. Vitamin D and calcium regulation of epidermal wound healing The Journal of Steroid Biochemistry and Molecular Biology · 2015 · 86 citations
    19. Role of Vitamin D and Calcium in Epidermal Wound Repair Wound healing · 2017 · 1 citations
    20. The Vitamin D Receptor Is a Wnt Effector that Controls Hair Follicle Differentiation and Specifies Tumor Type in Adult Epidermis PloS one · 2008 · 127 citations
    21. The Vitamin D Receptor as Tumor Suppressor in Skin Advances in experimental medicine and biology · 2020 · 55 citations
    22. Cloning of a Functional Vitamin D Receptor from the Lamprey (Petromyzon marinus), an Ancient Vertebrate Lacking a Calcified Skeleton and Teeth Endocrinology · 2003 · 104 citations
    23. The Tumor Suppressor Actions of the Vitamin D Receptor in Skin 2014 · 9 citations
    24. Vitamin D receptor is essential for normal keratinocyte stem cell function Proceedings of the National Academy of Sciences · 2007 · 143 citations
    25. Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice Endocrine reviews · 2008 · 1533 citations
    26. Vitamin D Receptor: Key Roles in Bone Mineral Pathophysiology, Molecular Mechanism of Action, and Novel Nutritional Ligands Journal of bone and mineral research · 2007 · 137 citations
    27. The Role of the Vitamin D Receptor in the Epidermal Stem Cell Response to Wounding Receptors · 2024
    28. The Role of Vitamin D and Its Receptor in Hair Follicle Biology Elsevier eBooks · 2017
    29. The Tumor Suppressor Actions of the Vitamin D Receptor in Skin 2013
    30. Faculty Opinions recommendation of The vitamin D receptor is a Wnt effector that controls hair follicle differentiation and specifies tumor type in adult epidermis. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2008